ArticlePloS one2019
Noninvasive technique to evaluate the muscle fiber characteristics using q-space imaging.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
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- Rapid Deep Vat Printing Using Photoclickable Collagen-Based Bioresins.Advanced healthcare materials · 2025Article
- Time series analysis of ex-vivo ischemia-reperfused heart using Q-space imaging.Scientific reports · 2025Article
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- Characteristics of T2* and anisotropy parameters in inguinal and epididymal adipose tissues after cold exposure in mice.Scientific reports · 2024Article
- Muscle structure assessment using synchrotron radiation X-ray micro-computed tomography in murine with cerebral ischemia.Scientific reports · 2024Article
- Identifying the potential therapeutic effects of miR‑6516 on muscle disuse atrophy.Molecular medicine reports · 2024Article
- Potential of Lycii Radicis Cortex as an Ameliorative Agent for Skeletal Muscle Atrophy.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Influence of Diffusion Time and Temperature on Restricted Diffusion Signal: A Phantom Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Article
- Fiber-type traps: revisiting common misconceptions about skeletal muscle fiber types with application to motor control, biomechanics, physiology, and biology.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Review
- Article
- Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Identifies Abnormal Calf Muscle-Specific Energetics in Peripheral Artery Disease.Circulation. Cardiovascular imaging · 2022Article
- Laurel Attenuates Dexamethasone-Induced Skeletal Muscle Atrophy In Vitro and in a Rat Model.Nutrients · 2022Article
- Possibility for Visualizing the Muscle Microstructure by q-Space Imaging Technique.Applied bionics and biomechanics · 2022Article
- Detecting Mild Lower-limb Skeletal Muscle Fatigue with Stimulated-echo q-space Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2021Article
- MRI in the assessment of adipose tissues and muscle composition: how to use it.Quantitative imaging in medicine and surgery · 2020Review
- A non-volitional skeletal muscle endurance test measures functional changes associated with impaired blood flow.Journal of rehabilitation and assistive technologies engineeringArticle
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSkeletal muscles include fast and slow muscle fibers. The tibialis anterior muscle (TA) is mainly composed of fast muscle fibers, whereas the soleus muscle (SOL) is mainly composed of slow muscle fibers. However, a noninvasive approach for appropriately investigating the characteristics of muscles is not available. Monitoring of skeletal muscle characteristics can help in the evaluation of the effects of strength training and diseases on skeletal muscles. PURPOSE: The present study aimed to determine whether q-space imaging can distinguish between TA and SOL in in vivo mice.
methodsIn vivo magnetic resonance imaging of the right calves of mice (n = 8) was performed using a 7-Tesla magnetic resonance imaging system with a cryogenic probe. TA and SOL were assessed. q-space imaging was performed with a field of view of 10 mm × 10 mm, matrix of 48 × 48, and section thickness of 1000 μm. There were ten b-values ranging from 0 to 4244 s/mm2, and each b-value had diffusion encoding in three directions. Magnetic resonance imaging findings were compared with immunohistological findings.
resultsFull width at half maximum and Kurtosis maps of q-space imaging showed signal intensities consistent with immunohistological findings for both fast (myosin heavy chain II) and slow (myosin heavy chain I) muscle fibers. With regard to quantification, both full width at half maximum and Kurtosis could represent the immunohistological findings that the cell diameter of TA was larger than that of SOL (P < 0.01).
conclusionq-space imaging could clearly differentiate TA from SOL using differences in cell diameters. This technique is a promising method to noninvasively estimate the fiber type ratio in skeletal muscles, and it can be further developed as an indicator of muscle characteristics.
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