Evidence map›Paper›PMID 30946870›Full record

ArticleCancer letters2019

Mutant p53

Kishore Polireddy, Kanchan Singh, Melissa Pruski, Neal C Jones, Naveen V Manisundaram, Pavani Ponnela, Michel Ouellette, George Van Buren, Mamoun Younes, John S Bynon and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer.Journal of experimental & clinical cancer research : CR · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Kishore PolireddyDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas McGovern Medical School, Houston, TX, 77030, USA.
Kanchan SinghDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas McGovern Medical School, Houston, TX, 77030, USA.
Melissa PruskiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas McGovern Medical School, Houston, TX, 77030, USA.
Neal C JonesDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas McGovern Medical School, Houston, TX, 77030, USA.
Naveen V ManisundaramDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas McGovern Medical School, Houston, TX, 77030, USA.
Pavani PonnelaDivision of Immunology and Organ Transplantation, Department of Surgery, The University of Texas McGovern Medical School, Houston, TX, 77030, USA.
Michel OuelletteDivision of Gastroenterology, Department of Internal Medicine, The University of Nebraska Medical Center, Omaha, NE, 68198, USA.
George Van BurenDivision of Surgical Oncology, Department of Surgery, Baylor College of Medicine, Houston, TX, 77030, USA.
Mamoun YounesDivision of Pathology and Laboratory Medicine, The University of Texas McGovern Medical School, Houston, TX, 77030, USA.
John S BynonDivision of Surgical Oncology, Department of Surgery, Baylor College of Medicine, Houston, TX, 77030, USA.
Wasim A DarDivision of Surgical Oncology, Department of Surgery, Baylor College of Medicine, Houston, TX, 77030, USA.
Jennifer M BaileyDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The University of Texas McGovern Medical School, Houston, TX, 77030, USA. Electronic address: Jennifer.M.Bailey@uth.tmc.edu.
Baylor College of Medicine · USThe University of Texas Health Science Center at Houston · USUniversity of Nebraska Medical Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3M
SHORT TERM RESEARCH TRAININGT35DK007676 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KONE, BRUCE C. · 1992 to 2017
$1.8M
NCI NIH HHS P30 CA016672NIDDK NIH HHS P30 DK056338NIDDK NIH HHS T35 DK007676
6 · The paper itself

Abstract

Pancreatic cancer remains a highly lethal malignancy. We have recently shown that simultaneous expression of Kras and mutant Tp53

Indexed as

CarcinogenesisCell Line, TumorCell NucleusCell SurvivalHSP70 Heat-Shock ProteinsHumansMutationPancreatic NeoplasmsProteomicsTumor Suppressor Protein p53HSP70 Heat-Shock ProteinsTP53 protein, humanTumor Suppressor Protein p53Pancreatic cancerProteomics

Identifiers

PMID30946870
PMCPMC9753970
OpenAlexW2930224352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.