Evidence map›Paper›PMID 30946774›Full record

ArticlePloS one2019

The French version of the HSCL-25 has now been validated for use in primary care.

Patrice Nabbe, Jean Yves Le Reste, Morgane Guillou-Landreat, Florence Gatineau, Bernard Le Floch, Tristan Montier, Harm Van Marwijk, Paul Van Royen

Registry-linked trialAbstract readMulticenter StudyValidation Study
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02414711 (Validation of the French Translation of the Scale HSCL25 in the Diagnosis of Depression in Primary Care), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02414711 nacompletednot on this map

Validation of the French Translation of the Scale HSCL25 in the Diagnosis of Depression in Primary Care

TypeinterventionalSponsorUniversity Hospital, BrestRan2015 to 2016Enrolled1,128ConditionsDepressionArmsHSCL25 scale, PSE9 questionary
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
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  6. Establishing the Association Between Snus Use and Mental Health Problems: A Study of Norwegian College and University Students.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  7. Does Time Heal Trauma? 18 Month Follow-Up Study of Syrian Refugees' Mental Health in Iraq's Kurdistan Region.International journal of environmental research and public health · 2022
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patrice NabbeEA 7479 SPURBO, Department of general practice, Université de Bretagne Occidentale, Brest, France.ORCID 0000-0002-2489-6476
Jean Yves Le ResteEA 7479 SPURBO, Department of general practice, Université de Bretagne Occidentale, Brest, France.
Morgane Guillou-LandreatEA 7479 SPURBO, Department of addictology, Université de Bretagne Occidentale, Brest, France.
Florence GatineauEA 7479 SPURBO, Department of general practice, Université de Bretagne Occidentale, Brest, France.
Bernard Le FlochEA 7479 SPURBO, Department of general practice, Université de Bretagne Occidentale, Brest, France.
Tristan MontierUnité INSERM 1078, SFR 148 ScInBioS, Université de Bretagne Occidentale, Brest, France.
Harm Van MarwijkDivision of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester I Williamson Building, Oxford Road, Manchester, United Kingdom.ORCID 0000-0001-6206-485X
Paul Van RoyenDepartment of Primary and Interdisciplinary Care, Faculty of Medicine and Health Sciences, Universiteit Antwerpen, Antwerpen, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Hopkins Symptom Checklist in 25 items (HSCL-25) helps to assess anxiety and depression in Primary Care. Anxiety and depression show considerable overlap in primary care. This self-administrated questionnaire is valid, reliable and ergonomic in the original US version. We have translated it into French. The aim of this study was to estimate the test characteristics of the HSCL-25, in its French version (F-HSCL-25), by comparing it to the Present State Examination-9 French version (F-PSE-9) and by determining its internal validity and dimensions.

methodOutpatients from three French General Practice settings (rural, semi-rural and urban) were recruited: approximately 20,000 outpatients among 17 GPs. Two groups were formed: F-HSCL-25 ≥1.75 and F-HSCL-25 <1.75. A validated cut-off score of > 1.75 was considered to indicate a clinically relevant level of symptoms of depression and anxiety. In order to obtain two balanced groups, a different method of randomization was chosen for each group. The F-PSE-9 was randomly administered to 1 in 2 patients in the F-HSCL-25 ≥1.75 group, and to 1 in 16 in the (much larger) F-HSCL-25 <1.75 group. The diagnostic performance was assessed and the test results obtained from both groups were compared with their F-PSE-9 results.

resultsOf the 1126 patients who completed the F-HCL-25, 886 joined the F-HSCL-25 <1.75 group and 240 the F-HSCL-25 ≥1.75 group. The overall prevalence of depression, using the F-HSCL-25, was 21% in these medical practices. The diagnostic performance of the F-HSCL-25 versus the F-PSE-9, the external criteria were as follows: Positive Predictive Value (PPV) 69.8%, Negative Predictive Value (NPV) 87%; Sensitivity 59.1%, and Specificity 91.4%. The Principal Component Analysis showed that F-HSCL-25 is a one-dimensional tool (anxiety and depression dimensions combined) with a Cronbach Alpha of 0.93.

conclusionThe F-HSCL-25 is an appropriate diagnostic tool for anxiety and depression in primary care in France due to its high specificity and high NPV. The HSCL-25 scale has a high eigenvalue. This pilot study will be extended throughout Europe; however, preliminary evidence suggests that the HSCL-25 is a reliable and suitable diagnostic tool for primary care.

Indexed as

Primary Health CareSurveys and QuestionnairesAdolescentAdultAgedAged, 80 and overAnxietyDepressionFemaleFranceHumansMaleMiddle AgedPilot ProjectsPsychometricsReproducibility of Results

Identifiers

PMID30946774
PMCPMC6448853

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.