Evidence map›Paper›PMID 30946762›Full record

ArticlePloS one2019

Rapid habituation of a touch-induced escape response in Zebrafish (Danio rerio) Larvae.

Adam C Roberts, Julia Chornak, Joseph B Alzagatiti, Duy T Ly, Brent R Bill, Janie Trinkeller, Kaycey C Pearce, Ronny C Choe, C S Campbell, Dustin Wong and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Adam C RobertsDepartment of Psychology, California State University at Fullerton, Fullerton, CA, United States of America.
Julia ChornakDepartment of Neuroscience, University of California, Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0002-8008-4325
Joseph B AlzagatitiDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Duy T LyDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0001-9366-1366
Brent R BillDepartment of Biology, University of Texas at Tyler, Tyler, TX, United States of America.
Janie TrinkellerDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Kaycey C PearceDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Ronny C ChoeDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0002-6180-1210
C S CampbellDepartment of Psychology, California State University at Fullerton, Fullerton, CA, United States of America.ORCID 0000-0002-0569-0712
Dustin WongDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.
Emily DeutschDepartment of Psychology, California State University at Fullerton, Fullerton, CA, United States of America.ORCID 0000-0003-0143-8525
Sarah HernandezDepartment of Psychology, California State University at Fullerton, Fullerton, CA, United States of America.ORCID 0000-0001-8028-3642
David L GlanzmanDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, United States of America.

Funding

PLASTICITY AT SENSORIMOTOR SYNAPSES IN CULTURER01NS029563 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GLANZMAN, DAVID L · 1992 to 2017
$2.6M
NINDS NIH HHS R01 NS029563
6 · The paper itself

Abstract

Zebrafish larvae have several biological features that make them useful for cellular investigations of the mechanisms underlying learning and memory. Of particular interest in this regard is a rapid escape, or startle, reflex possessed by zebrafish larvae; this reflex, the C-start, is mediated by a relatively simple neuronal circuit and exhibits habituation, a non-associative form of learning. Here we demonstrate a rapid form of habituation of the C-start to touch that resembles the previously reported rapid habituation induced by auditory or vibrational stimuli. We also show that touch-induced habituation exhibits input specificity. This work sets the stage for in vivo optical investigations of the cellular sites of plasticity that mediate habituation of the C-start in the larval zebrafish.

Indexed as

Habituation, PsychophysiologicAnimalsElectroshockEscape ReactionGlycineHeadLarvaReflex, StartleStrychnineTouchZebrafishGlycineStrychnine

Identifiers

PMID30946762
PMCPMC6449028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.