Evidence map›Paper›PMID 30946490›Full record

ArticleTransfusion2019

Implementation of a script for predonation interviews: impact on human immunodeficiency virus risk in South African blood donors.

Josephine Mitchel, Brian Custer, Zhanna Kaidarova, Edward L Murphy, Karin van den Berg, Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) South Africa Program

Open access · greenAbstract read
In one paragraph

Article in Transfusion, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Josephine MitchelSouth African National Blood Service, Johannesburg, South Africa.
Brian CusterVitalant Research Institute, San Francisco, California.ORCID 0000-0001-6251-366X
Zhanna KaidarovaVitalant Research Institute, San Francisco, California.
Edward L MurphyVitalant Research Institute, San Francisco, California.
Karin van den BergSouth African National Blood Service, Johannesburg, South Africa.
Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) South Africa Program
South African National Blood Service · ZAUniversity of California, San Francisco · USPacific Research Institute · US

Funding

Int'l Traineeships in AIDS Prevention Studies (ITAPS)R25MH064712 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LINDAN, CHRISTINA P · 2002 to 2018
$3.4M
Research training in HIV-related transfusion medicine and hematology in South AfricaD43TW010345 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI UTE JENTSCH, EDWARD L MURPHY · 2017 to 2026
$3.0M
International Traineeships in AIDS Prevention Studies (ITAPS)R25MH123256 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTINA P LINDAN · 2020 to 2026
$1.8M
FIC NIH HHS D43 TW010345FIC NIH HHS D43-TW010345NHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INIMH NIH HHS R25 MH064712NIMH NIH HHS R25MH064712NIMH NIH HHS R25 MH123256
6 · The paper itself

Abstract

backgroundThe way in which the donor history questionnaire is conducted plays a crucial role in the self-disclosure of behavioral risk factors for human immunodeficiency virus (HIV) infection by prospective donors. The South African National Blood Service changed its policy on the process of donor assessment in May 2015 by implementing a compulsory interviewer script used to assess donor eligibility. STUDY DESIGN AND

methodsA pre- and postevaluation study to determine the impact of scripted interviews on high-risk deferrals and recently acquired HIV infections. We used historical data to compare 18 months before and after the implementation of the script.

resultsWe recorded a total of 3,169,656 donor presentations during the two 18-months periods, of which 52.2% (1,655,352) were made during the scripted period. A multivariable logistic regression analysis adjusting for donor and demographic characteristics found the odds of high-risk deferral to be slightly greater (odds ratio [OR], 1.06; 95% confidence interval [CI], 1.05-1.07) during the scripted period. A separate multivariate logistic regression model, also adjusting for donor and demographic characteristics, showed that the odds of recently acquired HIV infection were significantly lower (OR, 0.88; 95% CI, 0.79-0.97) during the scripted period.

conclusionThis study showed that implementation of a scripted interview was associated with increased HIV risk deferral and decreased recent HIV infection. This study indicates potential improvement in blood safety with the implementation of a scripted donor interview and has relevance to blood safety in other sub-Saharan African countries.

Indexed as

Black PeopleBlood DonorsBlood SafetyHIV-1Surveys and QuestionnairesAdultFemaleHIV InfectionsHumansMaleMiddle AgedSouth Africa

Identifiers

PMID30946490
PMCPMC6610781
OpenAlexW2926374106

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.