Evidence map›Paper›PMID 30946213›Full record

ArticleTransplantation2020

Enhanced Advocacy and Health Systems Training Through Patient Navigation Increases Access to Living-donor Kidney Transplantation.

Jayme E Locke, Rhiannon D Reed, Vineeta Kumar, Beverly Berry, Daagye Hendricks, Alexis Carter, Brittany A Shelton, Margaux N Mustian, Paul A MacLennan, Haiyan Qu and 3 more

Open access · greenAbstract read
In one paragraph

Article in Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

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  17. Mandating COVID-19 vaccination prior to kidney transplantation in the United States: No solutions, only decisions.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jayme E LockeUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Rhiannon D ReedUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Vineeta KumarUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Beverly BerryUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Daagye HendricksUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Alexis CarterUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Brittany A SheltonUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Margaux N MustianUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Paul A MacLennanUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Haiyan QuUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Lonnie HannonDepartment of Biology, Center for Cancer Research, Tuskegee University, Tuskegee, AL.
Clayton YatesDepartment of Biology, Center for Cancer Research, Tuskegee University, Tuskegee, AL.
Michael J HanawayUniversity of Alabama at Birmingham School of Medicine, Comprehensive Transplant Institute, Birmingham, AL.
Miami Transplant Institute · USUniversity of Alabama at Birmingham · US

Funding

Tuskegee University Center for Biomedical Research/ Research Centers at Minority InstitutionsU54MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI Clayton Yates · 2017 to 2026
$29.4M
INFRASTRUCTURE IIG12MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI YATES, CLAYTON · 2012 to 2016
$4.6M
NIMHD NIH HHS G12 MD007585NIMHD NIH HHS U54 MD007585
6 · The paper itself

Abstract

backgroundTo date, no living donation program has simultaneously addressed the needs of both transplant candidates and living donors by separating the advocacy role from the candidate and improving potential donor comfort with the evaluation process. We hypothesized that the development of a novel program designed to promote both advocacy and systems training among transplant candidates and their potential living kidney donors would result in sustained increases in living-donor kidney transplantation (LDKT). To this end, we developed and implemented a Living Donor Navigator (LDN) Program at the University of Alabama at Birmingham.

methodsWe included adult patients awaiting kidney-only transplant in a retrospective cohort analysis. Using time-varying Cox proportional hazards regression, we explored likelihood of living donor screening and approval by participation in the LDN program.

resultsThere were 56 LDN participants and 1948 nonparticipants (standard of care). LDN was associated with a 9-fold increased likelihood of living donor screenings (adjusted hazard ratio, 9.27; 95% confidence interval, 5.97-14.41, P < 0.001) and a 7-fold increased likelihood of having an approved living donor (adjusted hazard ratio, 7.74; 95% confidence interval, 3.54-16.93; P < 0.001) compared with the standard of care. Analyses by participant race demonstrated higher likelihood of screened donors and a similar likelihood of having an approved donor among African Americans compared with Caucasians.

conclusionsThese data suggest that both advocacy and systems training are needed to increase actual LDKT rates, and that LDN programs may mitigate existing racial disparities in access to LDKT.

Indexed as

Kidney TransplantationPatient AdvocacyPatient NavigationAlabamaBlack or African AmericanDonor SelectionFemaleHealthcare DisparitiesHealth Services AccessibilityHumansLiving DonorsMaleMiddle AgedProgram EvaluationRetrospective StudiesWhite People

Identifiers

PMID30946213
PMCPMC6773517
OpenAlexW2931431039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.