Evidence map›Paper›PMID 30946179›Full record

ReviewCurrent opinion in nephrology and hypertension2019

Updates in the management of heart failure for the chronic kidney disease patient.

Simon Hsu, Nisha Bansal

Abstract readReview
In one paragraph

Review in Current opinion in nephrology and hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Simon HsuDepartment of Medicine/Division of Nephrology, Kidney Research Institute, University of Washington, Seattle, Washington, USA.
Nisha Bansal

Funding

RESEARCH TRAINING IN RENAL DISEASET32DK007467 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA, KESTENBAUM, BRYAN R · 1986 to 2023
$5.1M
Heart failure and atrial arrhythmias in CKDR01DK103612 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA · 2015 to 2018
$1.9M
NIDDK NIH HHS R01 DK103612NIDDK NIH HHS T32 DK007467
6 · The paper itself

Abstract

purpose of reviewHeart failure is highly prevalent in patients with chronic kidney disease (CKD) and a leading cause of morbidity and mortality in this population. Heart failure therapies proven to benefit the general population may have different risk-benefit profiles in patients with concurrent CKD, plausibly because of the unique pathophysiology of heart failure in this population. The present review highlights recent advances in heart failure treatment as they apply to patients with CKD. RECENT

findingsSeveral recent publications have shown possible benefits of established heart failure therapies to improve clinical outcomes in patients with CKD; while others conclude neutral or even harmful effects of heart failure therapies in CKD patients. Novel heart failure therapies show promise to improve outcomes in the general population and should be evaluated in future studies to further elucidate the efficacy and safety of these novel therapies specifically in patients with CKD. SUMMARY: Knowledge of heart failure treatment to improve clinical outcomes in the CKD population remains limited. Future studies should focus on patients with CKD to evaluate the generalizability of heart failure therapies to this patient population.

Indexed as

Defibrillators, ImplantableHeart FailureHumansMineralocorticoid Receptor AntagonistsNeprilysinRenal Insufficiency, ChronicSodium-Glucose Transporter 2 InhibitorsMineralocorticoid Receptor AntagonistsNeprilysinSodium-Glucose Transporter 2 Inhibitors

Identifiers

PMID30946179
PMCPMC6625663

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.