Evidence map›Paper›PMID 30946160›Full record

ArticleAIDS (London, England)2019

Work and home productivity of people living with HIV in Zambia and South Africa.

Ranjeeta Thomas, Rocco Friebel, Kerrie Barker, Lawrence Mwenge, Sarah Kanema, Nosivuyile Vanqa, Abigail Harper, Nomtha Bell-Mandla, Peter C Smith, Sian Floyd and 6 more

Open access · hybridAbstract read
In one paragraph

Article in AIDS (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 3 countries.

Ranjeeta ThomasDepartment of Health Policy, London School of Economics and Political Science.
Rocco FriebelDepartment of Health Policy, London School of Economics and Political Science.
Kerrie BarkerFaculty of Medicine, Imperial College London, London, UK.
Lawrence MwengeZAMBART Project, Ridgeway Campus, University of Zambia, Lusaka, Zambia.
Sarah KanemaZAMBART Project, Ridgeway Campus, University of Zambia, Lusaka, Zambia.
Nosivuyile VanqaDesmond Tutu TB Centre, Stellenbosch University, Department of Paediatrics and Child Health, Tygerberg Campus, Cape Town.
Abigail HarperDivision of Epidemiology and Biostatistics, University of the Witwatersrand, Johannesburg, South Africa.
Nomtha Bell-MandlaDesmond Tutu TB Centre, Stellenbosch University, Department of Paediatrics and Child Health, Tygerberg Campus, Cape Town.
Peter C SmithBusiness School, Imperial College London.
Sian FloydDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health.
Peter BockDesmond Tutu TB Centre, Stellenbosch University, Department of Paediatrics and Child Health, Tygerberg Campus, Cape Town.
Helen AylesDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine.
Sarah FidlerDepartment of Medicine.
Richard HayesDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health.
Katharina HauckDepartment of Infectious Disease Epidemiology, Imperial College London, London, UK.
HPTN 071 (PopART) Study Team
Imperial College London · GBDesmond Tutu HIV Foundation · ZALondon School of Economics and Political Science · GBUniversity of Zambia · ZMLondon School of Hygiene & Tropical Medicine · GBStellenbosch University · ZAUniversity of the Witwatersrand · ZA

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
Medical Research Council MR/R010161/1Medical Research Council MR/R015600/1NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619PEPFAR
6 · The paper itself

Abstract

objectiveTo compare number of days lost to illness or accessing healthcare for HIV-positive and HIV-negative individuals working in the informal and formal sectors in South Africa and Zambia.

designAs part of the HPTN 071 (PopART) study, data on adults aged 18-44 years were gathered from cross-sectional surveys of random general population samples in 21 communities in Zambia and South Africa. Data on the number of productive days lost in the last 3 months, laboratory-confirmed HIV status, labour force status, age, ethnicity, education, and recreational drug use was collected.

methodsDifferences in productive days lost between HIV-negative and HIV-positive individuals ('excess productive days lost') were estimated with negative binomial models, and results disaggregated for HIV-positive individuals after various durations on antiretroviral treatment (ART).

resultsFrom samples of 19 330 respondents in Zambia and 18 004 respondents in South Africa, HIV-positive individuals lost more productive days to illness than HIV-negative individuals in both countries. HIV-positive individuals in Zambia lost 0.74 excess productive days [95% confidence interval (CI) 0.48-1.01; P < 0.001] to illness over a 3-month period. HIV-positive in South Africa lost 0.13 excess days (95% CI 0.04-0.23; P = 0.007). In Zambia, those on ART for less than 1 year lost most days, and those not on ART lost fewest days. In South Africa, results disaggregated by treatment duration were not statistically significant.

conclusionThere is a loss of work and home productivity associated with HIV, but it is lower than existing estimates for HIV-positive formal sector workers. The findings support policy makers in building an accurate investment case for HIV interventions.

Indexed as

EfficiencyAdolescentAdultBiostatisticsCross-Sectional StudiesFemaleHIV InfectionsHumansMaleSouth AfricaYoung AdultZambia

Identifiers

PMID30946160
PMCPMC6467557
OpenAlexW2912692886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.