Evidence map›Paper›PMID 30945762›Full record

ArticleBioelectromagnetics2019

Effects of 50 Hz magnetic fields on circadian rhythm control in mice.

Louise Lundberg, Zenon Sienkiewicz, Daniel C Anthony, Kerry A Broom

Open access · hybridAbstract read
In one paragraph

Article in Bioelectromagnetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Louise LundbergPublic Health England, Chilton, United Kingdom.
Zenon SienkiewiczPublic Health England, Chilton, United Kingdom.
Daniel C AnthonyDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Kerry A BroomPublic Health England, Chilton, United Kingdom.ORCID http://orcid.org/0000-0003-2421-5076
Public Health England · GBUniversity of Oxford · GB

Funding

Public Health England
6 · The paper itself

Abstract

Artificial light and power frequency magnetic fields are ubiquitous in the built environment. Light is a potent zeitgeber but it is unclear whether power frequency magnetic fields can influence circadian rhythm control. To study this possibility, 8-12-week-old male C57BL/6J mice were exposed for 30 min starting at zeitgeber time 14 (ZT14, 2 h into the dark period of the day) to 50 Hz magnetic fields at 580 μT using a pair of Helmholtz coils and/or a blue LED light at 700 lux or neither. Our experiments revealed an acute adrenal response to blue light, in terms of increased adrenal per1 gene expression, increased serum corticosterone levels, increased time spent sleeping, and decreased locomotor activity (in all cases, P < 0.0001) compared to an unexposed control group. There appeared to be no modulating effect of the magnetic fields on the response to light, and there was also no effect of the magnetic fields alone (in both cases, P > 0.05) except for a decrease in locomotor activity (P < 0.03). Gene expression of the cryptochromes cry1 and cry2 in the adrenals, liver, and hippocampus was also not affected by exposures (in all cases, P > 0.05). In conclusion, these results suggest that 50 Hz magnetic fields do not significantly affect the acute light response to a degree that can be detected in the adrenal response. Bioelectromagnetics. 2019;9999:XX-XX. © 2019 Bioelectromagnetics Society.

Indexed as

Circadian RhythmAnimalsCorticosteroneCryptochromesGene Expression RegulationLightMagnetic FieldsMaleMice, Inbred C57BLMotor ActivityOrgan SpecificityPeriod Circadian ProteinsSleepCorticosteroneCryptochromesPer1 protein, mousePeriod Circadian Proteinsanimalsbehaviorbiological clockclock genesELF

Identifiers

PMID30945762
PMCPMC6617993
OpenAlexW2928728262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.