Evidence map›Paper›PMID 30945728›Full record

ArticleInternational journal of epidemiology2019

Socio-economic inequalities in life expectancy of older adults with and without multimorbidity: a record linkage study of 1.1 million people in England.

Mei Sum Chan, Ardo van den Hout, Mar Pujades-Rodriguez, Melvyn Mark Jones, Fiona E Matthews, Carol Jagger, Rosalind Raine, Madhavi Bajekal

Open access · hybridAbstract read
In one paragraph

Article in International journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 59 citations in OpenAlex.

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  6. Regional and gender disparities in depression and late life expectancy in Chile.Social psychiatry and psychiatric epidemiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Mei Sum ChanDepartment of Applied Health Research, University College London, London, UK.
Ardo van den HoutDepartment of Statistical Science, University College London, London, UK.
Mar Pujades-RodriguezHealth Science Research, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Melvyn Mark JonesResearch Department of Primary Care and Population Health, UCL Medical School, London, UK.
Fiona E MatthewsInstitute of Health and Society, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Carol JaggerInstitute of Health and Society, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Rosalind RaineDepartment of Applied Health Research, University College London, London, UK.
Madhavi BajekalDepartment of Applied Health Research, University College London, London, UK.
University College London · GBNewcastle Hospitals - Campus for Ageing and Vitality · GBUniversity of Leeds · GBUniversity of Oxford · GB

Funding

Medical Research Council MR/N011775/1
6 · The paper itself

Abstract

backgroundAge of onset of multimorbidity and its prevalence are well documented. However, its contribution to inequalities in life expectancy has yet to be quantified.

methodsA cohort of 1.1 million English people aged 45 and older were followed up from 2001 to 2010. Multimorbidity was defined as having 2 or more of 30 major chronic diseases. Multi-state models were used to estimate years spent healthy and with multimorbidity, stratified by sex, smoking status and quintiles of small-area deprivation.

resultsUnequal rates of multimorbidity onset and subsequent survival contributed to higher life expectancy at age 65 for the least (Q1) compared with most (Q5) deprived: there was a 2-year gap in healthy life expectancy for men [Q1: 7.7 years (95% confidence interval: 6.4-8.5) vs Q5: 5.4 (4.4-6.0)] and a 3-year gap for women [Q1: 8.6 (7.5-9.4) vs Q5: 5.9 (4.8-6.4)]; a 1-year gap in life expectancy with multimorbidity for men [Q1: 10.4 (9.9-11.2) vs Q5: 9.1 (8.7-9.6)] but none for women [Q1: 11.6 (11.1-12.4) vs Q5: 11.5 (11.1-12.2)]. Inequalities were attenuated but not fully attributable to socio-economic differences in smoking prevalence: multimorbidity onset was latest for never smokers and subsequent survival was longer for never and ex smokers.

conclusionsThe association between social disadvantage and multimorbidity is complex. By quantifying socio-demographic and smoking-related contributions to multimorbidity onset and subsequent survival, we provide evidence for more equitable allocation of prevention and health-care resources to meet local needs.

Indexed as

Life ExpectancyMultimorbiditySocioeconomic FactorsAgedAged, 80 and overChronic DiseaseCohort StudiesEnglandFemaleHealth StatusHumansMaleMiddle AgedPoverty AreasRisk FactorsSmokinghealth expectancyinequalitiesmortalityMultimorbiditymulti-state modelling

Identifiers

PMID30945728
PMCPMC6693817
OpenAlexW2919188527

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.