Evidence map›Paper›PMID 30945673›Full record

ArticleJournal of genetics2019

Genomewide association study for C-reactive protein in Indians replicates known associations of common variants.

Gauri Prasad, Anil K Giri, Indico Consortium, Analabha Basu, Nikhil Tandon, Dwaipayan Bharadwaj

Abstract read
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In one paragraph

Article in Journal of genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Gauri PrasadGenomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology, New Delhi 110 020, India. nikhil_tandon@hotmail.com,db@jnu.ac.in.
Anil K Giri
Indico Consortium
Analabha Basu
Nikhil Tandon
Dwaipayan Bharadwaj
Institute of Genomics and Integrative Biology · INAll India Institute of Medical Sciences · INJawaharlal Nehru University · INNational Institute of Biomedical Genomics · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated C-reactive protein (CRP) serves as an independent biomarker for acute and chronic inflammation, and is also associated with metabolic diseases. Genomewide loci regulating CRP level in Indian population, a high-risk group for metabolic illness, is unexplored. Therefore, we aimed to discover common polymorphisms associated with plasma CRP level in 4493 Indians of Indo-European origin using genomewide association study. Genomewide strong associations of two known intronic variants in hepatocyte nuclear factor-1 α gene (

Indexed as

Genome-Wide Association StudyPolymorphism, Single NucleotideAdultBiomarkersCase-Control StudiesC-Reactive ProteinFemaleFollow-Up StudiesHumansIndiaInflammationMaleMetabolic DiseasesMiddle AgedPrognosisRisk FactorsBiomarkersC-Reactive Protein

Identifiers

PMID30945673
OpenAlexW2915127147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.