Evidence map›Paper›PMID 30945239›Full record

ArticleJournal of ultrasound2019

Treatment of thyroid nodules with radiofrequency: a 1-year follow-up experience.

Paolo Rabuffi, Antonio Spada, Daniela Bosco, Antonio Bruni, Simone Vagnarelli, Cesare Ambrogi, Enrico Di Stasio, Assunta Santonati

Open access · bronzeAbstract read
In one paragraph

Article in Journal of ultrasound, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. RFA and benign thyroid nodules: Review of the current literature.Laryngoscope investigative otolaryngology · 2021
    Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Paolo RabuffiDepartment of Interventional Radiology, San Giovanni Addolorata Hospital, Rome, Italy. paolorabuffi@gmail.com.ORCID http://orcid.org/0000-0001-7261-2717
Antonio SpadaDepartment of Endocrinology, Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy.
Daniela BoscoDepartment of Endocrinology, Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy.
Antonio BruniDepartment of Interventional Radiology, San Giovanni Addolorata Hospital, Rome, Italy.
Simone VagnarelliDepartment of Interventional Radiology, San Giovanni Addolorata Hospital, Rome, Italy.
Cesare AmbrogiDepartment of Interventional Radiology, San Giovanni Addolorata Hospital, Rome, Italy.
Enrico Di StasioFondazione Policlinico Universitario A. Gemelli-IRCCS, Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy.
Assunta SantonatiDepartment of Endocrinology, Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy.
Azienda Ospedaliera San Giovanni Addolorata · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to assess the effectiveness and safety of radiofrequency ablation (RFA) in debulking benign solid thyroid nodules. MATERIALS AND

methodsThis is a retrospective review of 77 patients with predominantly solid thyroid nodules treated with RFA in a single center between 2013 and 2016. All patients declined or were not eligible for surgery. Benign proven thyroid nodules causing compressive symptoms and cosmetic concerns were considered for treatment. Nodule volume, thyroid nodule related compressive symptoms, cosmetic concerns and thyroid function were evaluated.

resultsAll patients underwent a single treatment session. Mean nodule volume decreased from 17.9 ± 15.6 mL at baseline to 5.2 ± 7.4 after 12 months with a volume reduction ratio (VRR) of 70.9% ± 20.8%. There were no identifiable factors predictive of response to RFA. Median cosmetic and symptom scores of the entire population decreased from 3 [2-4] and 3 [0-10] to 1 [1-3] (p < 0.001) and 0 [0-5] (p < 0.001), respectively. No major complications occurred and RFA did not affect thyroid function when normal.

conclusionRFA induces substantial volume reduction of predominantly solid thyroid nodules and improves compressive symptoms and cosmetic concerns. RFA does not impact normal thyroid function and has an acceptable safety profile.

Indexed as

Radiofrequency AblationAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedOrgan SizeRetrospective StudiesThyroid NoduleTreatment OutcomeBenign thyroid nodules.Minimally invasive techniquesRadiofrequency ablationThermal ablation therapy

Identifiers

PMID30945239
PMCPMC6531559
OpenAlexW2935602532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.