Evidence map›Paper›PMID 30945145›Full record

ArticleNeurochemical research2020

The negative effect of magnetic nanoparticles with ascorbic acid on peritoneal macrophages.

Klára Jiráková, Maksym Moskvin, Lucia Machová Urdzíková, Pavel Rössner, Fatima Elzeinová, Milada Chudíčková, Daniel Jirák, Natalia Ziolkowska, Daniel Horák, Šárka Kubinová and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Klára JirákováDepartment of Neuroregeneration, Institute of Experimental Medicine, Czech Academy of Sciences, Vídeňská 1083, 142 20, Prague 4, Czech Republic.
Maksym MoskvinDepartment of Polymer Particles, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic.
Lucia Machová UrdzíkováDepartment of Neuroregeneration, Institute of Experimental Medicine, Czech Academy of Sciences, Vídeňská 1083, 142 20, Prague 4, Czech Republic.
Pavel RössnerDepartment of Genetic Toxicology and Nanotoxicology, Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.
Fatima ElzeinováDepartment of Genetic Toxicology and Nanotoxicology, Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.
Milada ChudíčkováDepartment of Biomaterials and Biophysical Methods, Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.
Daniel JirákMR-Unit, Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Natalia ZiolkowskaMR-Unit, Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Daniel HorákDepartment of Polymer Particles, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic.
Šárka KubinováDepartment of Biomaterials and Biophysical Methods, Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.
Pavla JendelováDepartment of Neuroregeneration, Institute of Experimental Medicine, Czech Academy of Sciences, Vídeňská 1083, 142 20, Prague 4, Czech Republic. Pavla.jendelova@iem.cas.cz.ORCID http://orcid.org/0000-0002-4644-9212
Czech Academy of Sciences · CZCzech Academy of Sciences, Institute of Macromolecular Chemistry · CZInstitute of Clinical and Experimental Medicine · CZ

Funding

Grantová Agentura České Republiky 16-14631SGrantová Agentura České Republiky 17-04918SMinisterstvo Školství, Mládeže a Tělovýchovy CZ.02.1.01/0.0. /0.0/15_003/0000419Ministerstvo Školství, Mládeže a Tělovýchovy LTAUSA17120
6 · The paper itself

Abstract

Superparamagnetic iron oxide nanoparticles (SPIOn) are widely used as a contrast agent for cell labeling. Macrophages are the first line of defense of organisms in contact with nanoparticles after their administration. In this study we investigated the effect of silica-coated nanoparticles (γ-Fe

Indexed as

AnimalsAntioxidantsAscorbic AcidCells, CulturedCell SurvivalDose-Response Relationship, DrugDrug SynergismFemaleMacrophages, PeritonealMagnetite NanoparticlesRatsRats, WistarAntioxidantsAscorbic AcidMagnetite NanoparticlesCytotoxicityMacrophagesNanoparticlesOxidative stress

Identifiers

PMID30945145
OpenAlexW2930053745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.