Evidence map›Paper›PMID 30945059›Full record

ArticleSurgical endoscopy2020

Opioid and non-opioid utilization at home following gastrointestinal procedures: a prospective cohort study.

Karsten Bartels, Katharine Mahoney, Kristen M Raymond, Shannon K McWilliams, Ana Fernandez-Bustamante, Richard Schulick, Christian J Hopfer, Susan K Mikulich-Gilbertson

2 registry-linked trialsAbstract read
In one paragraph

Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03034278 completednot on this map

Improving Opioid Prescription Safety After Surgery

TypeobservationalSponsorUniversity of Colorado, DenverRan2017 to 2021Enrolled785ConditionsOpioid UseArmsNot applicable - no intervention
NCT05221866 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficiency And Quality In Post-Surgical Pain Therapy After Discharge

TypeinterventionalSponsorUniversity of NebraskaRan2022 to 2023Enrolled711ConditionsOpioid Use, Opioid Dependence, Opioid Misuse, Post-Surgical ComplicationArmsEmpowering Patient to Steer Their Pain Management After Surgery, Provider-facing Prescription Aid
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. PostRegional anesthesia and pain medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karsten BartelsDepartment of Surgery, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA. karsten.bartels@ucdenver.edu.
Katharine MahoneyDepartment of Psychiatry, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA.
Kristen M RaymondDepartment of Psychiatry, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA.
Shannon K McWilliamsDepartment of Psychiatry, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA.
Ana Fernandez-BustamanteDepartment of Anesthesiology, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA.
Richard SchulickDepartment of Surgery, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA.
Christian J HopferDepartment of Psychiatry, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA.
Susan K Mikulich-GilbertsonDepartment of Psychiatry, University of Colorado/Anschutz Medical Campus, 12401 E. 17th Avenue, MS B-113, Aurora, CO, 80045, USA.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Improving Opioid Prescription Safety After SurgeryK23DA040923 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BARTELS, KARSTEN · 2016 to 2020
$945k
NCATS NIH HHS UL1 TR002535NIDA NIH HHS K23 DA040923
6 · The paper itself

Abstract

backgroundOverprescribing of opioid medications for patients to be used at home after surgery is common. We sought to ascertain important patient and procedural characteristics that are associated with low versus high rates of self-reported utilization of opioids at home, 1-4 weeks after discharge following gastrointestinal surgery.

methodsWe developed a survey consisting of questions from NIH PROMIS tools for pain intensity/interference and queries on postoperative analgesic use. Adult patients completed the survey weekly during the first month after discharge. Using regression procedures we determined the patient and procedure characteristics that predicted high post-discharge opioid use operationalized as 75 mg oral morphine equivalents/50 mg oxycodone reported taken.

resultsThe survey response rate was 86% (201/233). High opioid use was reported by 52.7% of patients (106/201). Median reported intake of opioid pain pills was 7 for week #1 and 0 for weeks #2-4. Combinations of acetaminophen and non-steroidal and anti-inflammatory drugs were used by 8.9%-12.5% of patients after discharge. Following adjustment for significant variables of the univariate analysis, last 24-h in-hospital opioid intake remained as a significant co-variate for post-discharge opioid intake.

conclusionsAfter gastrointestinal surgery, the equivalent of each oxycodone 5 mg tablet taken in the last 24 h before discharge increases the likelihood of taking the equivalent of > 10 oxycodone 5 mg tablets by 5%. Non-opioid analgesia was utilized in less than half of the cases. Maximizing non-opioid analgesic therapy and basing opioid prescriptions on 24-h pre-discharge opioid intake may improve the quality of post-discharge pain management.

Indexed as

Digestive System Surgical ProceduresAdultAnalgesics, Non-NarcoticAnalgesics, OpioidDrug Utilization ReviewFemaleHumansMaleMiddle AgedOpioid-Related DisordersPain ManagementPostoperative PainPractice Patterns, Physicians'Prospective StudiesUnited StatesAnalgesics, Non-NarcoticAnalgesics, OpioidAnalgesics, opioidDigestive system surgical proceduresPainPatient dischargeSelf-report

Identifiers

PMID30945059
PMCPMC6776715

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.