Evidence map›Paper›PMID 30944880›Full record

ArticlemSystems

Altered Bacterial-Fungal Interkingdom Networks in the Guts of Ankylosing Spondylitis Patients.

Ming Li, Bingbing Dai, Yawei Tang, Lei Lei, Ningning Li, Chang Liu, Teng Ge, Lilong Zhang, Yao Xu, Yuqi Hu and 4 more

Open access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. Environmental and Genetic Determinants of Ankylosing Spondylitis.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Ming Li *College of Basic Medical Science, Dalian Medical University, Dalian, China.
Bingbing Dai *Department of Rheumatology and Immunology, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Yawei TangCollege of Basic Medical Science, Dalian Medical University, Dalian, China.
Lei LeiDepartment of Rheumatology and Immunology, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Ningning LiDepartment of Rheumatology and Immunology, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Chang LiuDepartment of Rheumatology and Immunology, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China.
Teng GeLiaoning International Travel Health Care Center, Dalian, China.
Lilong ZhangCollege of Basic Medical Science, Dalian Medical University, Dalian, China.
Yao XuCollege of Basic Medical Science, Dalian Medical University, Dalian, China.
Yuqi HuCollege of Basic Medical Science, Dalian Medical University, Dalian, China.
Pengfei LiCollege of Basic Medical Science, Dalian Medical University, Dalian, China.
Yan ZhangDepartment of Rheumatology and Immunology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Jieli YuanCollege of Basic Medical Science, Dalian Medical University, Dalian, China.
Xia LiCollege of Basic Medical Science, Dalian Medical University, Dalian, China.
Dalian Medical University · CNDalian Municipal Central Hospital · CNShenzhen International Travel Health Care Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal bacterial dysbiosis has been increasingly linked to ankylosing spondylitis (AS), which is a prototypic and best studied subtype of spondyloarthritis (SpA). Fungi and bacteria coexist in the human gut and interact with each other. Although they have been shown to contribute actively to health or disease, no studies have investigated whether the fungal microbiota in AS patients is perturbed. In this study, fecal samples from 22 AS patients, with clinical and radiographic assessments, and 16 healthy controls (HCs) were collected to systematically characterize the gut microbiota and mycobiota in AS patients by 16S rRNA gene- and ITS2-based DNA sequencing. Our results showed that the microbiota of AS patients was characterized by increased abundance of

Indexed as

ankylosing spondylitisdysbiosisinterkingdom networkmicrobiotamycobiota

Identifiers

PMID30944880
PMCPMC6435815
OpenAlexW2922912963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.