ArticlemSystems
Genomic Characterization and Virulence Potential of Two
Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Genomic description ofmSystems · 2025Article
- Microbiology of human spaceflight: microbial responses to mechanical forces that impact health and habitat sustainability.Microbiology and molecular biology reviews : MMBR · 2024Review
- Phylogenomics, phenotypic, and functional traits of five novel (Earth-derived) bacterial species isolated from the International Space Station and their prevalence in metagenomes.Scientific reports · 2023Article
- Phylogenetic affiliations and genomic characterization of novel bacterial species and their abundance in the International Space Station.Research square · 2023Article
- Characterization of metagenome-assembled genomes from the International Space Station.Microbiome · 2023Article
- Juxtaposing Caenorhabditis elegans-Pathogenic Mould Model with Other Models; How Reliable Is This Nematode Model? A Mini Review.Current microbiology · 2023Review
- Simulated Microgravity Created Using a Random Positioning Machine Induces Changes in the Physiology of theMicroorganisms · 2022Article
- The Isolation and Characterization of Rare Mycobiome Associated With Spacecraft Assembly Cleanrooms.Frontiers in microbiology · 2022Article
- Diversity of Microfungi in a High Radon Cave Ecosystem.Frontiers in microbiology · 2022Article
- Article
- Spatial Characterization of Microbial Communities on Multi-Species Leafy Greens Grown Simultaneously in the Vegetable Production Systems on the International Space Station.Life (Basel, Switzerland) · 2021Article
- Draft Genome Sequences of Fungi Isolated from the International Space Station during the Microbial Tracking-2 Experiment.Microbiology resource announcements · 2021Article
- Population genomics reveals historical and ongoing recombination in theStudies in mycology · 2021Article
- Advances in space microbiology.iScience · 2021Review
- Clinical Origin and Species Distribution ofJournal of fungi (Basel, Switzerland) · 2021Article
- Effects of Simulated Microgravity on the Proteome and Secretome of the Polyextremotolerant Black FungusFrontiers in genetics · 2021Article
- Comparative Genomic Analysis Provides Insights into the Phylogeny, Resistome, Virulome, and Host Adaptation in the GenusPathogens (Basel, Switzerland) · 2020Article
- Article
- Genomic and Functional Characterization ofFrontiers in microbiology · 2020Article
- Validating an Automated Nucleic Acid Extraction Device forFrontiers in microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Two isolates of Fusarium oxysporum, ISS-F3 and ISS-F4, were cultured from the dining table on the International Space Station (ISS). Genomic analyses using EF-1α sequences, presence/absence of effector proteins, k-mer comparisons, and single nucleotide polymorphisms indicate that these two strains are genomically different from 65 known sequenced strains. Functional analysis revealed that ISS-F3/F4 had higher relative abundances of polyketide synthase domains than a non-plant-pathogenic soil isolate, used for biocontrol properties (Fo47), and a clinical isolate (FOSC-3a). Putative secondary metabolite analysis indicates that ISS-F3/F4 may produce yet-unreported polyketides and nonribosomal peptides. While genomic analysis showed that these ISS strains are unlikely to be plant pathogens, a virulence assay using an immunocompromised Caenorhabditis elegans model of fusariosis revealed that they were virulent and may represent opportunistic pathogens in animals, including humans. However, its effects on the health of immunocompromised humans warrant further study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.