ArticleScience advances2019
Real-time interactive simulations of large-scale systems on personal computers and cell phones: Toward patient-specific heart modeling and other applications.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Real-time GPU-accelerated coupled cardiac system: Integrating bidirectional interactions between living optogenetic monolayers and computational simulations.PLoS computational biology · 2026Article
- Single-cell chiral symmetry breaking under confinement.bioRxiv : the preprint server for biology · 2026Article
- Article
- CardioFit: a WebGL-based tool for fast and efficient parametrization of cardiac action potential models to fit user-provided data.Royal Society open science · 2025Article
- Fast interactive simulations of cardiac electrical activity in anatomically accurate heart structures by compressing sparse uniform cartesian grids.Computer methods and programs in biomedicine · 2024Article
- Lipomatous Metaplasia Facilitates Ventricular Tachycardia in Patients With Nonischemic Cardiomyopathy.JACC. Clinical electrophysiology · 2024Article
- VisualPDE: Rapid Interactive Simulations of Partial Differential Equations.Bulletin of mathematical biology · 2023Article
- A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement.Scientific reports · 2023Article
- Fiber Organization Has Little Effect on Electrical Activation Patterns During Focal Arrhythmias in the Left Atrium.IEEE transactions on bio-medical engineering · 2023Article
- Article
- A smoothed boundary bidomain model for cardiac simulations in anatomically detailed geometries.PloS one · 2023Article
- Lipomatous Metaplasia Enables Ventricular Tachycardia by Reducing Current Loss Within the Protected Corridor.JACC. Clinical electrophysiology · 2022Article
- The physics of heart rhythm disorders.Physics reports · 2022Article
- Terminating spiral waves with a single designed stimulus: Teleportation as the mechanism for defibrillation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Voltage-mediated mechanism for calcium wave synchronization and arrhythmogenesis in atrial tissue.Biophysical journal · 2022Article
- Pacemaking function of two simplified cell models.PloS one · 2022Article
- Fast Characterization of Inducible Regions of Atrial Fibrillation Models With Multi-Fidelity Gaussian Process Classification.Frontiers in physiology · 2022Article
- Current progress of computational modeling for guiding clinical atrial fibrillation ablation.Journal of Zhejiang University. Science. B · 2021Review
- Detecting spiral wave tips using deep learning.Scientific reports · 2021Article
- Unimapper: An Online Interactive Analyzer/Visualizer of Optical Mapping Experimental Data.Computing in cardiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Cardiac dynamics modeling has been useful for studying and treating arrhythmias. However, it is a multiscale problem requiring the solution of billions of differential equations describing the complex electrophysiology of interconnected cells. Therefore, large-scale cardiac modeling has been limited to groups with access to supercomputers and clusters. Many areas of computational science face similar problems where computational costs are too high for personal computers so that supercomputers or clusters currently are necessary. Here, we introduce a new approach that makes high-performance simulation of cardiac dynamics and other large-scale systems like fluid flow and crystal growth accessible to virtually anyone with a modest computer. For cardiac dynamics, this approach will allow not only scientists and students but also physicians to use physiologically accurate modeling and simulation tools that are interactive in real time, thereby making diagnostics, research, and education available to a broader audience and pushing the boundaries of cardiac science.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.