Evidence map›Paper›PMID 30944845›Full record

ArticleApplied in vitro toxicology2019

Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements.

Troy D Hubbard, Jui-Hua Hsieh, Cynthia V Rider, Nisha S Sipes, Alexander Sedykh, Bradley J Collins, Scott S Auerbach, Menghang Xia, Ruili Huang, Nigel J Walker and 1 more

Abstract read
In one paragraph

Article in Applied in vitro toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Hepatotoxicity due to herbal dietary supplements: Past, present and the future.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
    Review
  7. Working with the natural complexity: Selection and characterization of black cohosh root extract for use in toxicology testing.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
    Article
  8. Review
  9. Article
  10. Improving natural product research translation: From source to clinical trial.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Troy D HubbardDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Jui-Hua HsiehKelly Government Solutions, Durham, North Carolina.
Cynthia V RiderDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Nisha S SipesDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Alexander SedykhSciome, Durham, North Carolina.
Bradley J CollinsDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Scott S AuerbachDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Menghang XiaNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
Ruili HuangNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
Nigel J WalkerDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Michael J DeVitoDivision of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.

Funding

Toxicological Assessments for the National Toxicology ProgramZIAES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2016 to 2019
$31.9M
Biomolecular Screening and Alternative Approaches for the National Toxicology ProgramZIAES103318 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI CASEY, WARREN · 2016 to 2021
$25.0M
Toxicology in the 21st Century Program (Tox21) - Systems ToxicologyZIATR000038 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI XIA, MENGHANG · 2015 to 2025
$5.7M
Toxicology in the 21st Century Program (Tox21) - Computational ToxicologyZIATR000040 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI HUANG, RUILI · 2016 to 2025
$3.5M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

botanical supplementsdietary supplementsin vitro screeningTox21toxicity

Identifiers

PMID30944845
PMCPMC6442399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.