ArticleIranian journal of basic medical sciences2019
The therapeutic effect of ozonated olive oil plus glucantime on human cutaneous leishmaniasis.
Article in Iranian journal of basic medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Plant-based therapeutics for leishmaniasis: A systematic review emphasizing human studies and clinical trial evidence.PLoS neglected tropical diseases · 2026Pooled it
- Risks of ozonated oil and ozonated water on human skin: A systematic review.International wound journal · 2022Pooled it
- The Effect of Ozone Therapy on Psoriasis.Clinical case reports · 2026Article
- Ozonated Sunflower Oil Stimulates the Local Antioxidant System and Helps Meglumine Antimoniate to Ameliorate Cutaneous Leishmaniasis Lesions.ACS omega · 2025Article
- Article
- Topical application of ozonated sunflower oil accelerates the healing of lesions of cutaneous leishmaniasis in mice under meglumine antimoniate treatment.Medical microbiology and immunology · 2024Article
- The Therapeutic Effect of Shirvan Herbal Ointment on Human Cutaneous Leishmaniasis Compared with Glucantime.Advanced biomedical research · 2024Article
- Treatment With Oxygen-Enriched Olive Oil Improves Healing Parameters Following Augmentation-Mastopexy.Aesthetic surgery journal. Open forum · 2021Article
- Ozonated Oils as Antimicrobial Systems in Topical Applications. Their Characterization, Current Applications, and Advances in Improved Delivery Techniques.Molecules (Basel, Switzerland) · 2020Review
- Effectiveness and Safety of Ozone Therapy for Dermatological Disorders: A Literature Review of Clinical Trials.Indian journal of dermatologyReview
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesLeishmaniasis is one of the main health problems in developing countries, caused by intracellular protozoan parasites of the Leishmania genus. Although research has been successful in discovering vaccines and anti-parasitic drugs like antimony compounds, their side effects like high toxicity, prolonged regeneration, etc., have raised the replacement importance of natural products with antioxidant and antibacterial properties. It can be said that an appropriate alternative to this is the ozonated olive oil. Ozone by introducing O MATERIALS AND
methodsThirty patients with confirmed leishmaniasis lesions were included and divided into two groups, 15 cases as control and 15 cases as test with lesions of 30-50 mm2 in diameter. The control group received glucantime intralesionally and the test group ozonated olive oil plus glucantime, 2 times daily.
resultsThe mean of lesion size was (50.94±33.20) before and (15±14.34) after treatment in control (
conclusionData suggested ozonated olive oil can have synergistic effects with glucantime in the treatment of cutaneous leishmaniasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.