ArticlePrzeglad gastroenterologiczny2019
Fibromatosis - immunohistochemical evaluation, differential diagnosis from gastrointestinal tumors, and other mesenchymal tumours.
Article in Przeglad gastroenterologiczny, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Management of high-risk (B3) breast lesions in symptomatic practice: evidence review and practical recommendations for multidisciplinary care.Virchows Archiv : an international journal of pathology · 2026Review
- Giant Desmoid Fibromatosis of the Small Bowel After Sleeve Gastrectomy: Case Report and Review of the Literature.Journal of personalized medicine · 2026Review
- Surgical management and immunohistochemical diagnosis of giant retroperitoneal tumors with spindle cell histology: a five-case case series.BMC surgery · 2026Article
- Management of Desmoid Tumors.Current oncology reports · 2025Review
- Challenges in Diagnosing Adolescent Goiter: A Case Report with Brief Literature Insights in Juvenile Desmoid-Type Fibromatosis of the Thyroid Gland.Journal of clinical medicine · 2025Review
- Retroperitoneal invasive fibromatosis after laparoscopic radical resection of colon cancer: a case report and literature review.Frontiers in oncology · 2025Article
- Non-IgG4-Related Fibrosing Mediastinitis Diagnosed on Core Needle Biopsy and Treated with Steroids: A Case Study and Review of the Differential Diagnoses.International journal of surgical pathology · 2024Review
- Annotating the Role ofNuclear medicine and molecular imaging · 2024Article
- A Rare Case of Inflammatory Myofibroblastic Tumor Mimicking Fibrous Adhesions Resulting in Bowel Obstruction.Case reports in surgery · 2024Article
- Retroperitoneal spindle cell tumor: a case report.Journal of surgical case reports · 2023Article
- Soft Tissue Reconstruction With Ovine Forestomach Matrix After Wide Excision of Plantar Fibromatosis.Eplasty · 2023Article
- Isolated Infratemporal Fossa Desmoid Fibromatosis: A Rare Case Report and Review of Literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Aggressive fibromatosis in the submandibular region of a child.Clinical case reports · 2022Article
- Surgical Management of a Giant Desmoid Fibromatosis of Abdominal Wall With Vessels Invasion in a Young Man: A Case Report and Review of the Literature.Frontiers in surgery · 2022Article
- Clinicopathological features of gastric inflammatory myofibroblastic tumor: Report of five cases.Experimental and therapeutic medicine · 2021Article
- Retroperitoneal Spindle Cell Tumor: A Case Report.Frontiers in surgery · 2021Article
- Clinicopathological features and differential diagnosis of gastrofibromatosis-like undifferentiated carcinoma.The Journal of international medical research · 2020Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFibromatosis is a histologically benign growth of fibroblastic and myofibroblastic cells, with a potential to recur and invade local organs. It can occur as a superficial or deep form. Visceral fibromatosis and superficial fibromatosis are histologically similar. They both have alterations in the WNT signalling pathway, but mutations in the APC or β-catenin gene do not occur in superficial fibromatoses.
aimTo present four cases of deep fibromatosis and one case of Peyronie's disease, along with immunohistochemical staining analysis and the criteria for differential diagnosis. MATERIAL AND
methodsAll patients were hospitalised in the Central Clinical Hospital of the MSWiA in Warsaw during the period of 2012-2015. Surgical specimens were examined, and tissue samples were embedded in paraffin blocks.
resultsAs the result of the study we present a short algorithm of immunostainings that can be useful in differential diagnosis. When a spindle cell tumour is encountered in the abdomen a gastrointestinal stromal tumor (GIST) should always be excluded; therefore, a CD117 staining is recommended as the first step. When the staining is negative, fibromatosis can be taken into consideration. β-Catenin staining should be done in order to confirm that diagnosis.
conclusionsThe diagnosis of fibromatosis is not always simple; GISTs can easily be mistaken for it. Immunohistochemical staining with CD34 and CD117 antibodies are useful in differential diagnosis. DTF should present negative stainings for S100, CD34, CD99, and bcl-2, which can help to distinguish it from other mesenchymal tumours.
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