ArticleInternational journal of endocrinology2019
Gender- and Age-Specific Differences in the Association of Hyperuricemia and Hypertension: A Cross-Sectional Study.
Article in International journal of endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Effectiveness and safety of different doses of febuxostat compared with allopurinol in the treatment of hyperuricemia: a meta-analysis of randomized controlled trials.BMC pharmacology & toxicology · 2023Pooled it
- Effect of sacubitril/valsartan on serum uric acid and blood pressure in patients with hypertension and asymptomatic hyperuricemia: A randomized clinical trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Previous schistosome infection and the risk of incident hyperuricemia: A prospective cohort study.PLoS neglected tropical diseases · 2026Article
- Association of exposure duration, modality, and polycythaemia with hyperuricaemia among han male immigrants at high altitudes: a cross-sectional study.Annals of medicine · 2025Article
- Higher cardiometabolic index elevates the risk of hyperuricemia in the elderly: findings from the China health and retirement longitudinal study.Annals of medicine · 2025Article
- Gender-specific association between serum uric acid levels and hypertension in East China: a cross-sectional study.BMC public health · 2025Article
- Beneficial and Detrimental Effects of Uric Acid on Alzheimer's Disease.Current neuropharmacology · 2025Review
- Gender-Specific Differences in Prevalence and Association of Cardio-Metabolic Parameters and Hyperuricemia: A Population-Based Cross-Sectional Study, Nakhon Nayok, Thailand.Iranian journal of public health · 2024Article
- Sex-specific associations between serum uric acid levels and risk of hypertension for different diagnostic reference values of high blood pressure.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Prevalence of Hyperuricemia and Rheumatoid Factor Positivity Among Patients Aged 35 and Above in Huye District, Southern Province of Rwanda.Open access rheumatology : research and reviews · 2024Article
- Gender-specific association between blood cell parameters and hyperuricemia in high-altitude areas.Frontiers in public health · 2024Article
- Association between cardiovascular health assessed by life's essential 8 and hyperuricemia in U.S. adults: the NHANES 2009-2020.Frontiers in endocrinology · 2024Article
- The relation between uric acid level and blood pressure values among patients hospitalized in a department of internal medicine.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2023Article
- Fatty Acid-Rich Extract fromMolecules (Basel, Switzerland) · 2023Article
- Exploring the mechanism underlying hyperuricemia using comprehensive research on multi-omics.Scientific reports · 2023Article
- Gene Dose-Dependent and Additive Effects ofMetabolites · 2022Article
- Gender and Age-Specific Differences in the Association of Thyroid Function and Hyperuricemia in Chinese: A Cross-Sectional Study.International journal of endocrinology · 2022Article
- High-Throughput Untargeted Serum Metabolomics Analysis of Hyperuricemia Patients by UPLC-Q-TOF/MS.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBoth hyperuricemia and hypertension have important clinical implications, but their relationship in terms of gender and age is still a matter of debate. In this study, we aimed to explore gender- and age-specific differences in this association between hyperuricemia and hypertension in a Chinese population.
methodsA total of 78596 ostensibly healthy subjects (47781 men and 30815 women) were recruited. The association between hyperuricemia and hypertension was analyzed by multivariate logistic regression, and the analyses were stratified by gender and age.
resultsOverall prevalence of hypertension and hyperuricemia was significantly higher in males than in females. Increasing trends of hypertension prevalence in both genders as well as hyperuricemia prevalence in females were found along with aging. However, males showed a reduced trend in hyperuricemia prevalence with aging. Higher hypertension and hyperuricemia prevalence was found in young and middle-aged men than in women, but not in elderly people older than 70 years. Significantly increased risk of hypertension from hyperuricemia was found only in men with an adjusted odds ratio of 1.131 (
conclusionWe observed significantly higher overall prevalence of hyperuricemia and hypertension in men than in women. Men with hyperuricemia (particularly in middle age) had a significantly increased susceptibility of hypertension, while this significant association was not observed in women.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.