Evidence map›Paper›PMID 30944548›Full record

ArticleMediators of inflammation2019

Huang Qi Tong Bi Decoction Attenuates Myocardial Ischemia-Reperfusion Injury via HMGB1/TLR/NF-

Kun Liu, Manman Li, Xiumei Ren, Qing-Sheng You, Fei Wang, Shuo Wang, Chun-Hui Ma, Wei-Nan Li, Qing Ye

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. D-Limonene mitigate myocardial injury in rats through MAPK/ERK/NF-κB pathway inhibition.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2020
    Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kun LiuDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Manman LiSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Xiumei RenDepartment of Traditional Chinese Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Qing-Sheng YouDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Fei WangDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Shuo WangDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Chun-Hui MaDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Wei-Nan LiDepartment of Cardiothoracic Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Qing YeDepartment of Obstetrics and Gynecology, Affiliated Hospital of Nantong University, Nantong, China.ORCID 0000-0001-6874-5146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to study the protective effect of Huang Qi Tong Bi Decoction (HQTBT) on the heart of rats. Ischemia-reperfusion injury was established by coronary artery ligation. Proinflammatory cytokines were decreased by XFZY in coronary artery ligated rats. ST segment was also restored with the treatment of HQTBT. Triphenyltetrazole chloride (TTC) staining and pathological analysis showed that HQTBT reduced myocardial injury. Besides, the expressions of HMGB1/TLR/NF-

Indexed as

AnimalsAstragalus propinquusDrugs, Chinese HerbalHMGB1 ProteinMaleMyocardial Reperfusion InjuryNF-kappa BRatsRats, Sprague-DawleySignal TransductionToll-Like ReceptorsDrugs, Chinese HerbalHMGB1 ProteinHuang QiNF-kappa BToll-Like Receptors

Identifiers

PMID30944548
PMCPMC6421754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.