Evidence map›Paper›PMID 30944459›Full record

ArticleEye (London, England)2019

Treatment of presumed trematode-induced granulomatous anterior uveitis among children in rural areas of Egypt.

Amgad El Nokrashy, Waleed Abou Samra, Doaa Sobeih, Ali Lamin, Aya Hashish, Sahar Tarshouby, Susan Lightman, Ashraf Sewelam

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Amgad El NokrashyMansoura Ophthalmic center, Mansoura University, Mansoura, Egypt. Amgad.ali@mans.edu.eg.
Waleed Abou SamraMansoura Ophthalmic center, Mansoura University, Mansoura, Egypt.
Doaa SobeihMansoura Ophthalmic Hospital, Ministry of Health, Mansoura, Egypt.
Ali LaminUCL/Institute of Ophthalmology, London, UK.ORCID http://orcid.org/0000-0003-4419-2326
Aya HashishMansoura Ophthalmic center, Mansoura University, Mansoura, Egypt.
Sahar TarshoubyMansoura Ophthalmic center, Mansoura University, Mansoura, Egypt.
Susan LightmanUCL/Institute of Ophthalmology, London, UK.
Ashraf SewelamMansoura Ophthalmic center, Mansoura University, Mansoura, Egypt.
Mansoura University · EGMoorfields Eye Hospital · GBHarvard University Press · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to evaluate the efficacy of systemic antiparasitic medications alone or in combination with surgical aspiration in management of presumed trematode-induced anterior uveitis in children. PATIENTS AND

methodsProspective case series. Children who presented with anterior chamber (AC) granuloma were included in the study. All patients received antiparasitic treatment and after 2 weeks; patients were divided based on their clinical improvement in terms of the baseline granuloma area into two groups: group A (<2.5 mm

resultsThirty eyes of 30 patients were included in the study with a mean age of 13.4 ± 2.42 years. All patients were male. Patients were examined and followed at Mansoura Ophthalmic Center, Mansoura University. Both groups showed statistically significant improvement in VA, AC activity, corneal thickness and granuloma area (p-value < 0.001), which was achieved with medical treatment only in group A. However, in group B granuloma required aspiration and did not recur after that.

conclusionPresumed trematode-induced AC granuloma is common among children living in the rural areas of Egypt. Antiparasitic medication alone was found to be effective for small-sized granulomas. Surgical aspiration is an effective adjuvant procedure to treat large-sized ones.

Indexed as

Ophthalmologic Surgical ProceduresAdolescentAnimalsAntiprotozoal AgentsChildChild, PreschoolCombined Modality TherapyCorneal PachymetryDrug Therapy, CombinationEgyptEye Infections, ParasiticFecesGranulomaHumansMaleMetronidazoleAntiprotozoal AgentsMetronidazolePraziquantel

Identifiers

PMID30944459
PMCPMC7002623
OpenAlexW2932890635

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.