Evidence map›Paper›PMID 30944410›Full record

ArticleScientific reports2019

3D Synthetic Peptide-based Architectures for the Engineering of the Enteric Nervous System.

Paola Brun, Annj Zamuner, Alessandro Peretti, Jessica Conti, Grazia M L Messina, Giovanni Marletta, Monica Dettin

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

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  15. Bio-Functionalized Chitosan for Bone Tissue Engineering.International journal of molecular sciences · 2021
    Article
  16. Persistent Herpes Simplex Virus Type 1 Infection of Enteric Neurons Triggers CD8Frontiers in cellular and infection microbiology · 2021
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Paola BrunDepartment of Molecular Medicine, University of Padova, Via Gabelli, 63, Padova, 35121, Italy.ORCID http://orcid.org/0000-0002-3279-9000
Annj ZamunerDepartment of Industrial Engineering, University of Padova, Via Marzolo, 9, Padova, 35131, Italy.
Alessandro PerettiDepartment of Industrial Engineering, University of Padova, Via Marzolo, 9, Padova, 35131, Italy.
Jessica ContiDepartment of Molecular Medicine, University of Padova, Via Gabelli, 63, Padova, 35121, Italy.
Grazia M L MessinaDepartment of Chemical Sciences, University of Catania, Via A. Doria, 6, Catania, 95125, Italy.
Giovanni MarlettaDepartment of Chemical Sciences, University of Catania, Via A. Doria, 6, Catania, 95125, Italy.
Monica DettinDepartment of Industrial Engineering, University of Padova, Via Marzolo, 9, Padova, 35131, Italy. monica.dettin@unipd.it.ORCID http://orcid.org/0000-0002-6823-3375
University of Padua · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Damage of enteric neurons and partial or total loss of selective neuronal populations are reported in intestinal disorders including inflammatory bowel diseases and necrotizing enterocolitis. To develop three-dimensional scaffolds for enteric neurons we propose the decoration of ionic-complementary self-assembling peptide (SAP) hydrogels, namely EAK or EAbuK, with bioactive motives. Our results showed the ability of EAK in supporting neuronal cell attachment and neurite development. Therefore, EAK was covalently conjugated to: RGD, (GRGDSP)

Indexed as

AnimalsCell DifferentiationCells, CulturedCell SurvivalEnteric Nervous SystemInsulin-Like Growth Factor IMiceNerve Growth FactorNeurogenesisNeuronsNeurotrophin 3PeptidesRNA, MessengerInsulin-Like Growth Factor INerve Growth FactorNeurotrophin 3PeptidesRNA, Messenger

Identifiers

PMID30944410
PMCPMC6447567
OpenAlexW2926490016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.