Evidence map›Paper›PMID 30944319›Full record

ArticleNature communications2019

Ca

Jesse B Yoder, Manu Ben-Johny, Federica Farinelli, Lakshmi Srinivasan, Sophie R Shoemaker, Gordon F Tomaselli, Sandra B Gabelli, L Mario Amzel

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Calcium interaction with Nav1.5 via FGF12A and CaM binding.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Calmodulin Mutations in Human Disease.Channels (Austin, Tex.) · 2023
    Review
  9. Feedback contributions to excitation-contraction coupling in native functioning striated muscle.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  10. BIOLOGICAL ANTIARRHYTHMICS-SODIUM CHANNEL INTERACTING PROTEINS.Transactions of the American Clinical and Climatological Association · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. NaStructure (London, England : 1993) · 2021
    Article
  15. Physiologically Relevant Free CaJournal of molecular biology · 2021
    Article
  16. Review
  17. Calmodulin Interactions with Voltage-Gated Sodium Channels.International journal of molecular sciences · 2021
    Review
  18. Finite element analysis predicts CaScientific reports · 2021
    Article
  19. Elementary mechanisms of calmodulin regulation of NaProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Properties of Calmodulin Binding to NaNeurochemical research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jesse B YoderDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Manu Ben-JohnyDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, 10032, USA.
Federica FarinelliDivision of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Lakshmi SrinivasanDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Sophie R ShoemakerDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Gordon F TomaselliDivision of Cardiology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Sandra B GabelliDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. gabelli@jhmi.edu.ORCID http://orcid.org/0000-0003-1205-5204
L Mario AmzelDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. mamzel@jhmi.edu.
Johns Hopkins University · USAlbert Einstein College of Medicine · USColumbia University · US

Funding

Life Science and Biomedical technology Research center at NSLS-II LSBRP41GM111244 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI MCSWEENEY, SEAN · 2014 to 2018
$16.4M
Translational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZACHOS, NICHOLAS CONSTANTINE · 2011 to 2020
$12.0M
Case Center for Synchrotron BiosciencesP30EB009998 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI CHANCE, MARK R · 2009 to 2018
$8.4M
Calmodulin Regulation Na Channels: From Function and Structure to DiseaseR01HL128743 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ALDRICH, RICHARD, AMZEL, L. MARIO · 2016 to 2019
$4.2M
NHLBI NIH HHS R01 HL128743NIBIB NIH HHS P30 EB009998NIDDK NIH HHS P30 DK089502NIGMS NIH HHS P41 GM111244NIH HHS HL128743
6 · The paper itself

Abstract

Skeletal muscle voltage-gated Na

Indexed as

Amino Acid MotifsAmino Acid SequenceArrhythmias, CardiacBinding SitesCalciumCalmodulinHumansModels, MolecularMuscle, SkeletalMutationNAV1.4 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelProtein BindingProtein ConformationProtein DomainsProtein Interaction Domains and MotifsCalciumCalmodulinNAV1.4 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelProtein IsoformsSCN4A protein, humanSCN5A protein, human

Identifiers

PMID30944319
PMCPMC6447637
OpenAlexW2930076337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.