Evidence map›Paper›PMID 30944213›Full record

ArticlemSphere2019

Bacterial Stabilization of a Panel of Picornaviruses.

Elizabeth R Aguilera, Y Nguyen, Jun Sasaki, Julie K Pfeiffer

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Single cell viral tagging ofGut microbes · 2025
    Article
  7. Article
  8. Review
  9. Journal of virology · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. T-Cell Receptor Sequences Identify Combined Coxsackievirus-International journal of molecular sciences · 2024
    Article
  15. Article
  16. Review
  17. Impact of the Microbiota on Viral Infections.Annual review of virology · 2023
    Review
  18. Article
  19. Detection of Influenza virus andbioRxiv : the preprint server for biology · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Elizabeth R AguileraDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Y NguyenDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jun SasakiDepartment of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Julie K PfeifferDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA Julie.Pfeiffer@UTSouthwestern.edu.
The University of Texas Southwestern Medical Center · USFujita Health University · JP

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
The influence of host barriers on viral quasispecies diversity and pathogenesisR01AI074668 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI PFEIFFER, JULIE K · 2008 to 2022
$6.0M
Enteric virus-microbiota interactionsR37AI074668 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Julie K Pfeiffer · 2023 to 2026
$2.5M
Genetics of bacteria-mediated viral co-infectionR21AI114927 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI PFEIFFER, JULIE K · 2015 to 2016
$444k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI074668NIAID NIH HHS R21 AI114927NIAID NIH HHS R37 AI074668NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

Several viruses encounter various bacterial species within the host and in the environment. Despite these close encounters, the effects of bacteria on picornaviruses are not completely understood. Previous work determined that poliovirus (PV), an enteric virus, has enhanced virion stability when exposed to bacteria or bacterial surface polysaccharides such as lipopolysaccharide. Virion stabilization by bacteria may be important for interhost transmission, since a mutant PV with reduced bacterial binding had a fecal-oral transmission defect in mice. Therefore, we investigated whether bacteria broadly enhance stability of picornaviruses from three different genera:

Indexed as

Hot TemperatureMicrobial InteractionsBacteriaCardiovirusEnterovirusKobuvirusMutationPicornaviridaePoliovirusSodium HypochloriteVirus InactivationSodium Hypochloritebacteriapicornavirusesstability

Identifiers

PMID30944213
PMCPMC6449606
OpenAlexW2926093693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.