Evidence map›Paper›PMID 30944186›Full record

ArticleJournal of clinical microbiology2019

Culture of Rectal Swab Specimens for Enteric Bacterial Pathogens Decreases Time to Test Result While Preserving Assay Sensitivity Compared to Bulk Fecal Specimens.

Sophonie Jean, Melanie L Yarbrough, Neil W Anderson, C A Burnham

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. OptimizingJournal of clinical microbiology · 2026
    Observational
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Constipation and hemolytic uremic syndrome.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sophonie JeanDepartment of Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Melanie L YarbroughDepartment of Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-2166-7552
Neil W AndersonDepartment of Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
C A BurnhamDepartment of Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA cburnham@wustl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diarrheal illness is a major cause of morbidity and mortality throughout the world, yet the etiologic agent of many cases of gastrointestinal illness remains unspecified, often due to the lack of convenient, timely, and sensitive diagnostic testing. Although bulk fecal specimens remain the recommended specimen type for enteric culture, rectal swabs may be an option preferred by clinicians and patients due to the convenience and timing of collection. However, the lack of data evaluating the sensitivity of rectal swabs compared to fecal specimens for detection of enteric pathogens precludes this specimen type from being recommended by national guidelines. In this study, we retrospectively reviewed 480 paired rectal swab and fecal specimens submitted for enteric culture to the Barnes-Jewish Hospital and St. Louis Children's Hospital microbiology laboratories in St. Louis, MO, from 2002 to 2017. We report 32% positivity of paired specimens with an overall agreement of 93% and Cohen's κ of 0.84 (95% confidence interval, 0.78 to 0.89). Additionally, we evaluated the time to result from the time of patient presentation to the health care setting and demonstrate that rectal swabs have a significantly shorter time to an actionable result than bulk fecal specimens (median, 67.4 h versus 78.4 h, respectively;

Indexed as

Bacterial Typing TechniquesGastrointestinal MicrobiomeAdolescentAdultAgedAged, 80 and overChildChild, PreschoolDiarrheaFecesFemaleGastroenteritisHumansMaleMiddle AgedRectumdiarrheaenteric culturefecal cupgastrointestinal illnessrectal swabstool culture

Identifiers

PMID30944186
PMCPMC6535583

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.