Trial reportJournal of immunology (Baltimore, Md. : 1950)2019
Identification and Characterization of Functional Human Monoclonal Antibodies to
Open access · bronzeAbstract readClinical TrialMulticenter Study
In one paragraph
Trial report in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 33 citations in OpenAlex.
- An mRNA-lipid nanoparticle vaccine targeting theMolecular therapy. Nucleic acids · 2026Article
- Development of novel Aotus nancymaae non-human primate model for the evaluation of Plasmodium vivax blood stage vaccines and immunoprophylactics.Malaria journal · 2026Article
- Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages.Nature communications · 2024Article
- The PvRBP2b-TfR1 interaction is not essential for reticulocytes invasion by Plasmodium vivax isolates from Cambodia.NPJ vaccines · 2024Article
- Structure-based design of a Plasmodium vivax Duffy-binding protein immunogen focuses the antibody response to functional epitopes.Protein science : a publication of the Protein Society · 2024Article
- Vaccines and monoclonal antibodies: new tools for malaria control.Clinical microbiology reviews · 2024Review
- Comparative transcriptomics reveal differential gene expression among Plasmodium vivax geographical isolates and implications on erythrocyte invasion mechanisms.PLoS neglected tropical diseases · 2024Article
- Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals.Cell host & microbe · 2023Article
- Human monoclonal antibodies inhibit invasion of transgenic Plasmodium knowlesi expressing Plasmodium vivax Duffy binding protein.Malaria journal · 2023Article
- Designing an effective malaria vaccine targeting Plasmodium vivax Duffy-binding protein.Trends in parasitology · 2023Review
- Genetic diversity and natural selection of Plasmodium vivax reticulocyte invasion genes in Ecuador.Malaria journal · 2023Article
- Naturally-acquired and Vaccine-induced Human Monoclonal Antibodies tobioRxiv : the preprint server for biology · 2023Article
- Inhibition of a malaria host-pathogen interaction by a computationally designed inhibitor.Protein science : a publication of the Protein Society · 2023Article
- Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil.The American journal of tropical medicine and hygiene · 2022Article
- Monoclonal antibodies for malaria prevention.Molecular therapy : the journal of the American Society of Gene Therapy · 2022Review
- Band 3-mediatedFrontiers in cellular and infection microbiology · 2022Article
- Article
- Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.Nature communications · 2021Article
- Progress towards the development of aExpert review of vaccines · 2021Review
- Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes.PLoS neglected tropical diseases · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 9 institutions in 5 countries.
Lenore L CariasCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
Sebastien DechavanneCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106.ORCID 0000-0001-9400-1976
Vanessa C NicoleteDepartment of Parasitology, University of Sao Paulo, 05508-000 Sao Paulo, Brazil.
Sokunthea SrengNational Center for Parasitology, Entomology and Malaria Control, 12101 Phnom Penh, Cambodia.
Seila SuonNational Center for Parasitology, Entomology and Malaria Control, 12101 Phnom Penh, Cambodia.
Chanaki AmaratungaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Rick M FairhurstLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Celia DechavanneCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
Samantha BarnesCenter for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, FL 33612.ORCID 0000-0002-4784-4409
Benoit WitkowskiMalaria Unit, Pasteur Institute in Cambodia, 12201 Phnom Penh, Cambodia.
Jean PopoviciMalaria Unit, Pasteur Institute in Cambodia, 12201 Phnom Penh, Cambodia.ORCID 0000-0002-3135-1175
Camille RoeschMalaria Unit, Pasteur Institute in Cambodia, 12201 Phnom Penh, Cambodia.
Edwin ChenDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0003-2477-3537
Marcelo U FerreiraDepartment of Parasitology, University of Sao Paulo, 05508-000 Sao Paulo, Brazil.ORCID 0000-0002-5293-9090
Niraj H ToliaDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
John H AdamsCenter for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, FL 33612.ORCID 0000-0003-3707-7979
Christopher L KingCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106; cxk21@case.edu.
Institut Pasteur du Cambodge · KHNational Institutes of Health · USCambodia National Malaria Center · KHCenter for Global Health · USUniversidade de São Paulo · BRUniversity of South Florida · USCleveland FES Center · USUniversité Paris Cité · FRWashington University in St. Louis · US
Funding
WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Immaculate Lillian Nankya · 1994 to 2026
$50.0MSugar-feeding behavior of the malaria vector Nyssorhynchus darlingi and development of effective attractive toxic sugar baits (ATSB) to increase intervention success in PeruU19AI089681 · NIAID · YALE UNIVERSITY · PI VINETZ, JOSEPH M. · 2010 to 2023
$20.1MTransmissionU19AI089686 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI KAZURA, JAMES WALTER · 2010 to 2016
$9.9MImmunological characterization of the P. vivax DBPR01AI064478 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2006 to 2023
$9.6MMechanisms of effective antibody neutralization of malaria parasitesZIAAI001236 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI TOLIA, NIRAJ · 2018 to 2025
$6.6MStructural Vaccinology and Design of Novel Imunogens for Malaria Vaccine DevelopmentR01AI137162 · NIAID · WASHINGTON UNIVERSITY · PI GOLDBERG, DANIEL E. · 2018 to 2022
$3.6MELUCIDATING & DISRUPTING PLASMODIUM RECEPTOR-LIGAND INTERACTIONSR56AI080792 · NIAID · WASHINGTON UNIVERSITY · PI TOLIA, NIRAJ H. · 2015 to 2015
$381kStrain-specific Immunity to Plasmodium vivax malariaI01BX001350 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI KING, CHRISTOPHER L · 2014 to 2024
–BLRD VA I01 BX001350Intramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI001236NIAID NIH HHS HHSN272201400018CNIAID NIH HHS P30 AI036219NIAID NIH HHS R01 AI064478NIAID NIH HHS R01 AI137162NIAID NIH HHS R56 AI080792NIAID NIH HHS U19 AI089681NIAID NIH HHS U19 AI089686
Abstract
PubMed holds no abstract for this paper.
Indexed as
Antibody SpecificityImmunologic MemoryAntibodies, BlockingAntibodies, MonoclonalAntigens, ProtozoanB-LymphocytesFemaleHumansMalaria, VivaxMalePlasmodium vivaxProtozoan ProteinsReceptors, Cell SurfaceAntibodies, BlockingAntibodies, MonoclonalAntigens, ProtozoanDuffy antigen binding protein, PlasmodiumProtozoan ProteinsReceptors, Cell Surface
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.