Evidence map›Paper›PMID 30944031›Full record

ArticleBMC research notes2019

Preliminary study on the expression of endothelial cell biology related genes in the liver of dengue virus infected mice treated with Carica papaya leaf juice.

Mohd Ridzuan Mohd Abd Razak, Nor Azrina Norahmad, Nur Hana Md Jelas, Bazilah Jusoh, Amirrudin Muhammad, Norazlan Mohmad Misnan, Murizal Zainol, Ravindran Thayan, Ami Fazlin Syed Mohamed

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Antiviral & platelet-protective properties ofThe Indian journal of medical research · 2022
    Article
  5. Nutrients · 2022
    Article
  6. Immunomodulatory Activities ofPathogens (Basel, Switzerland) · 2021
    Article
  7. Phytoconstituents as Lead Compounds for Anti-Dengue Drug Discovery.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mohd Ridzuan Mohd Abd RazakHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia. ridzuan@imr.gov.my.ORCID http://orcid.org/0000-0002-9589-5892
Nor Azrina NorahmadHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Nur Hana Md JelasHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Bazilah JusohHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Amirrudin MuhammadHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Norazlan Mohmad MisnanHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Murizal ZainolHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Ravindran ThayanInfectious Disease Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Ami Fazlin Syed MohamedHerbal Medicine Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
Institute for Medical Research · MY

Funding

Ministry of Health 16-010/NMRR-16-681-30564
6 · The paper itself

Abstract

objectiveThe purpose of this study was to profile and identify the endothelial cell biology related genes that are affected by dengue virus infection in the liver tissue of AG129 mice, with and without Carica papaya leaf juice treatment.

resultsThe dengue fever mouse model was established by intraperitoneal inoculation of dengue virus, New Guinea C strain at 2 × 10

Indexed as

Fruit and Vegetable JuicesAnimalsCaricaDengueDengue VirusEndothelial CellsGene Expression ProfilingLiverMicePhytotherapyPlant ExtractsPlant LeavesPlant ExtractsAG129 miceCarica papayaDengueEndothelial cell biologyGene expressionIn vivoLiverPlantsqRT-PCRVirus

Identifiers

PMID30944031
PMCPMC6448258
OpenAlexW2943562329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.