Evidence map›Paper›PMID 30943980›Full record

Trial reportLipids in health and disease2019

A randomized, controlled trial on the effects of almonds on lipoprotein response to a higher carbohydrate, lower fat diet in men and women with abdominal adiposity.

Paul T Williams, Nathalie Bergeron, Sally Chiu, Ronald M Krauss

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01792648 (Effects of Almond Intake on Atherogenic Lipoprotein Particles in Individuals With Increased Abdominal Adiposity), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01792648 nacompletednot on this map

Effects of Almond Intake on Atherogenic Lipoprotein Particles in Individuals With Increased Abdominal Adiposity

TypeinterventionalSponsorUCSF Benioff Children's Hospital OaklandRan2013 to 2016Enrolled24ConditionsDyslipidemia, Obesity, AbdominalArmsStandard reference diet, Almond supplemented diet, Low carbohydrate reference diet
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paul T WilliamsChildren's Hospital Oakland Research Institute, Oakland, California, USA.
Nathalie BergeronChildren's Hospital Oakland Research Institute, Oakland, California, USA.
Sally ChiuChildren's Hospital Oakland Research Institute, Oakland, California, USA.
Ronald M KraussChildren's Hospital Oakland Research Institute, Oakland, California, USA. rkrauss@chori.org.
Touro University California · US

Funding

Almond Board of California (US) Krauss-R01
6 · The paper itself

Abstract

backgroundAlmonds have been shown to lower LDL cholesterol but there is limited information regarding their effects on the dyslipidemia characterized by increased levels of very low density lipoproteins (VLDL) and small, dense low-density lipoprotein (LDL) particles that is associated with abdominal adiposity and high carbohydrate intake. The objective of the present study was to test whether substitution of almonds for other foods attenuates carbohydrate-induced increases in small, dense LDL in individuals with increased abdominal adiposity.

methodsThis was a randomized cross-over study of three 3wk diets, separated by 2wk washouts: a higher-carbohydrate (CHO) reference diet (CHO

resultsRelative to the CHO

conclusionOur analyses provided no evidence that deriving 20% E from almonds significantly modifies increases in levels of small, dense LDL or other plasma lipoprotein changes induced by a higher carbohydrate low saturated fat diet in individuals with increased abdominal adiposity.

trial registrationClinicaltrials.gov NCT01792648 .

Indexed as

Prunus dulcisAdiposityAdultCardiovascular DiseasesCholesterol, LDLDietary CarbohydratesDietary FatsDiet, Fat-RestrictedEnergy IntakeFemaleHumansLipoproteinsLipoproteins, VLDLMaleMiddle AgedObesity, AbdominalCholesterol, LDLDietary CarbohydratesDietary FatsLipoproteinsLipoproteins, VLDLTriglyceridesAlmondsHigh carbohydrateLipidsLipoprotein sizeTriglycerides

Identifiers

PMID30943980
PMCPMC6446393
OpenAlexW2947678669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.