Evidence map›Paper›PMID 30943969›Full record

ArticleBMC endocrine disorders2019

Adherence to antidiabetic medication and factors associated with non-adherence among patients with type-2 diabetes mellitus in two regional hospitals in Cameroon.

Leopold Ndemnge Aminde, Maxime Tindong, Calypse A Ngwasiri, Jeannine A Aminde, Tsi Njim, Azingala Ajua Fondong, Noah Fongwen Takah

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Article in BMC endocrine disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leopold Ndemnge AmindeFaculty of Medicine, School of Public Health, The University of Queensland, Brisbane, QLD, 4006, Australia. amindeln@gmail.com.ORCID http://orcid.org/0000-0003-2787-7518
Maxime TindongFaculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium.
Calypse A NgwasiriNon-communicable diseases Unit, Clinical Research Education, Networking and Consultancy, Douala, Cameroon.
Jeannine A AmindeEtoug-Ebe Baptist Hospital Yaounde (EBHY), Yaounde, Cameroon.
Tsi NjimDepartment of International Public Health, Liverpool School of Tropical Medicine, Pembroke Pl, Liverpool, L3 5QA, UK.
Azingala Ajua FondongFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Noah Fongwen TakahDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus is a growing cause of disease burden globally. Its management is multifaceted, and adherence to pharmacotherapy is known to play a significant role in glycaemic control. Data on medication adherence among affected patients is unknown in Cameroon. In this study, the level of adherence and factors influencing non-adherence to antidiabetic medication among patients with type-2 diabetes was assessed.

methodsA hospital-based cross-sectional study among adult patients receiving care in the diabetic clinics of the Limbe and Bamenda Regional Hospitals in Cameroon was conducted. Medication adherence was assessed using the Medication Compliance Questionnaire (MCQ). Factors associated with non-adherence to medication were determined using basic and adjusted multivariable logistic regression models.

resultsA total of 195 patients with type 2 diabetes were recruited. The prevalence of non-adherence to medication was 54.4% [95% confidence interval (CI): 47.1-61.5%]. In multivariable analysis, age > 60 years (aO.R. = 0.48, 95% CI: 0.25-0.94), alcohol consumption (aO.R. = 2.13, 95% CI: 1.10-4.14) and insulin alone therapy (aO.R. = 2.85, 95% CI: 1.01-8.08) were associated with non-adherence. Patients attributed their non-adherence to forgetfulness (55.6%), lack of finances (38.2%) and disappearance of symptoms (14.2%).

conclusionsAdherence to anti-diabetic medication is poor in this study with more than half of participants being non-adherent. Urgent interventions are required to tackle this problem in combined efforts to stem this looming diabetes epidemic.

Indexed as

Drug MonitoringBiomarkersCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansHypoglycemic AgentsMaleMedication AdherenceMiddle AgedPrognosisSurveys and QuestionnairesBiomarkersHypoglycemic AgentsCameroonMedication adherenceType 2 diabetes

Identifiers

PMID30943969
PMCPMC6446302

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.