ArticleBMC infectious diseases2019
Lactococcus garvieae, an unusual pathogen in infective endocarditis: case report and review of the literature.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 57 citations in OpenAlex.
- Phenotypic and phylogenomic characterization of Lactococcus garvieae isolates from rainbow trout (Oncorhynchus mykiss) in Türkiye.Veterinary research communications · 2026Article
- Infective endocarditis due toJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2026Article
- First Report of Concurrent Infective Endocarditis and Spondylitis Caused byAnnals of laboratory medicine · 2026Article
- First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe.Journal of fish diseases · 2026Article
- Lactococcus garvieae prosthetic aortic and mitral valve endocarditis with multiple embolic complications: a case report.Access microbiology · 2026Article
- Prevalence of bovine tuberculosis and attention zones for Mycobaterium bovis in the state of São Paulo (SP), Brazil, based on data from sanitary inspections at slaughterhouses.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Urinary Tract Infection Caused by Lactococcus garvieae in a 75-Year-Old Male Patient With a Complex Medical History.Cureus · 2025Article
- Infectious intracranial aneurysm associated withInfectious medicine · 2024Article
- A "fishy" situation, rare pathogen and presentation in prosthetic valve infective endocarditis.Heliyon · 2024Article
- Genomic investigation ofMicrobiology spectrum · 2024Article
- Redefining piscine lactococcosis.Applied and environmental microbiology · 2024Article
- Infective endocarditis caused byIDCases · 2024Article
- The Controversial Nature of Some Non-Starter Lactic Acid Bacteria Actively Participating in Cheese Ripening.Biotech (Basel (Switzerland)) · 2023Review
- Antimicrobial-Resistant Bacteria from Free-Living Green Turtles (Antibiotics (Basel, Switzerland) · 2023Article
- Comparative Genomic Analyses of Lactococcus garvieae Isolated from Bovine Mastitis in China.Microbiology spectrum · 2023Article
- Article
- Prevalence, Virulence, and Antibiotics Gene Profiles inMicroorganisms · 2023Article
- Lactococcus garvieae, an unusual etiology of prosthetic valve endocarditis. First case reported in Mexico.Archivos de cardiologia de Mexico · 2023Article
- Lactococcus endocarditis after Bentall procedure presenting with intracranial hemorrhage.IDCases · 2023Article
- Evidence of pediatric sepsis caused by a drug resistantEmerging microbes & infections · 2022Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundLactococcus garvieae is an unusual cause of infective endocarditis (IE). No current diagnostic and therapeutic guidelines are available to treat IE caused by these organisms. Based on a case report, we provide a review of the literature of IE caused by L. garvieae and highlight diagnostic and treatment challenges of these infections and implications for management. CASE PRESENTATION: A 50-year-old Asian male with mitral prosthetic valve presented to the hospital with intracranial haemorrhage, which was successfully treated. Three weeks later, he complained of generalized malaise. Further work up revealed blood cultures positive for Gram-positive cocci identified as L. garvieae by MALDI-TOF. An echocardiogram confirmed the diagnosis of IE. Susceptibility testing showed resistance only to clindamycin. Vancomycin plus gentamicin were started as empirical therapy and, subsequently, the combination of ceftriaxone plus gentamicin was used after susceptibility studies were available. After two weeks of combination therapy, ceftriaxone was continued as monotherapy for six additional weeks with good outcome.
conclusionsTwenty-five cases of IE by Lactococcus garvieae have been reported in the literature. Compared to other Gram-positive cocci, L. garvieae affects more frequently patients with prosthetic valves. IE presents in a subacute manner and the case fatality rate can be as high as 16%, comparable to that of streptococcal IE (15.7%). Reliable methods for identification of L. garvieae include MALDI-TOF, 16S RNA PCR, API 32 strep kit and BD Automated Phoenix System. Recommended antimicrobials for L. garvieae IE are ampicillin, amoxicillin, ceftriaxone or vancomycin in monotherapy or in combination with gentamicin.
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