ArticleBMC infectious diseases2019
Predictors of virological treatment failure among adult HIV patients on first-line antiretroviral therapy in Woldia and Dessie hospitals, Northeast Ethiopia: a case-control study.
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 7 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Pooled it
- Factors associated with unsuppressed HIV viral load among children under 15 years in sub-Saharan africa: a systematic review.AIDS research and therapy · 2025Pooled it
- Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023.HIV research & clinical practice · 2025Pooled it
- Onset and predictors of first-line antiretroviral therapy treatment failure among children in Ethiopia: a systematic review and meta-analysis.BMC pediatrics · 2024Pooled it
- Pooled it
- Effects of undernutrition on mortality and morbidity among adults living with HIV in sub-Saharan Africa: a systematic review and meta-analysis.BMC infectious diseases · 2021Pooled it
- Factors associated with antiretroviral treatment failure among people living with HIV on antiretroviral therapy in resource-poor settings: a systematic review and metaanalysis.Systematic reviews · 2020Pooled it
- Improvements in Patient-Reported Outcomes After 12 Months of Maintenance Therapy With Cabotegravir + Rilpivirine Long-Acting Compared With Bictegravir/Emtricitabine/Tenofovir Alafenamide in the Phase 3b SOLAR Study.AIDS and behavior · 2025Trial
- Trial
- Virological failure in HIV-naïve patients with antiretroviral therapy: A perspective from pharmacological variablesBiomedica : revista del Instituto Nacional de Salud · 2026Observational
- Viral load suppression and associated factors following enhanced adherence counseling among people living with HIV/AIDS.BMC infectious diseases · 2026Article
- Determinants of virologic failure among adult HIV patients on first-line antiretroviral therapy in health facilities of Awi Zone, northwest Ethiopia: a case-control study.AIDS research and therapy · 2026Article
- Cabotegravir+rilpivirine long-acting every 2 months in a real-world setting: 24-month outcomes in people with HIV-1.AIDS (London, England) · 2026Article
- Predicting HIV viral non-suppression in Uganda: development and validation of machine learning and risk stratification models using routine EMR data.Frontiers in artificial intelligence · 2026Article
- Viral failure and associated factors in adults on second line antiretroviral therapy in public hospitals of Harari Region and Dire Dawa administration, Eastern Ethiopia.Journal of public health research · 2025Article
- Article
- Under-nutrition and its associated factors among adult second-line antiretroviral treatment users in Northern Ethiopia.BMC public health · 2025Article
- Virological treatment failure and associated factors among adults on first-line antiretroviral therapy in West Hararghe, Ethiopia.Frontiers in public health · 2025Article
- Incidence Rate, Survival Rate, and Predictors for Virological Failure Among Adult TB/HIV Coinfected Clients.Journal of tropical medicine · 2025Article
- Social, economic and food insecurity among people living with HIV in Kenya during coinciding public health and environmental emergencies: a mixed-methods study.BMJ public health · 2024Article
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Abstract
backgroundVirological treatment failure is a problem that a Human Immune Virus patient faces after starting treatment due to different factors. However, there were few studies done on the predictors of virological treatment failure among adult patients on first-line antiretroviral therapy in Ethiopia in general, and no study was done in the study area in particular. Therefore, the aim of the study was to identify predictors of virological treatment failure among adult patients on first-line antiretroviral therapy in Woldiya and Dessie Hospitals, Northeast Ethiopia.
methodHospital based case-control study was conducted in Woldia and Dessie Hospitals from from 12 August 2016-28 February 2018 on 154 cases and 154 controls among adult patients on first-line antiretroviral treatment. All cases were included and comparable controls were selected using stratified random sampling technique. Data were collected by document review using checklists and entered into Epidata version 3.1 and analyzed by SPSS version 21. Multivariable logistic regression analysis was done to identify the independent predictors of virological treatment failure.
resultsIn this study, statistically higher odds of virological failure was observed among patients who had current CD4 T-cell count of < 200 mm
conclusionThis study showed that low current CD4 T-cell count and body mass index, as well as poor adherence for ART treatment predicts virological failure. Therefore, deliberate efforts are urgently needed in HIV care through improving their nutritional status by enhancing nutritional education and support, and by strengthening enhanced adherence counseling.
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