ArticleAnnals of pediatric endocrinology & metabolism2019
Reference range of random urinary calcium creatinine ratio in North Indian children and adolescents.
Article in Annals of pediatric endocrinology & metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Efficacy, safety, and dose-response effects of calcifediol supplementation on 25-hydroxyvitamin D, parathyroid hormone, and 1,25-dihydroxyvitamin D levels in healthy adults: An open-label, interventional pilot study.Indian journal of pharmacologyTrial
- Normal Reference Range of the Urinary Calcium/Creatinine Ratio in Healthy Children.Indian journal of pediatrics · 2026Article
- Spot Urine Calcium to Creatinine Ratio: Age-Specific Reference Ranges.Indian journal of pediatrics · 2026Article
- Greater Urinary Calcium Excretion Is Associated With Diminished Bone Accrual in Youth With Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2025Observational
- Calcium, Phosphorus, and Vitamin D Levels in a Series of Cystic Fibrosis Patients: A Cross-Sectional Study.International journal of molecular sciences · 2024Article
- Association of dietary intake with micronutrient deficiency in Indian school children: a cross-sectional study.Journal of nutritional science · 2023Article
- Calcium status assessment at the population level: Candidate approaches and challenges.Annals of the New York Academy of Sciences · 2022Review
- Evaluating Vitamin D Status in Infants Less than Seven Months; What Are the Preferred Biochemical Measurements?Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2022Article
- The spectrum of manifestations of primary hyperparathyroidism in children and adolescents.Pediatric endocrinology, diabetes, and metabolism · 2022Article
- Application of a six sigma model to evaluate the analytical performance of urinary biochemical analytes and design a risk-based statistical quality control strategy for these assays: A multicenter study.Journal of clinical laboratory analysis · 2021Article
- Diagnosis and management of X-linked hypophosphatemia in children and adolescent in the Gulf Cooperation Council countries.Archives of osteoporosis · 2021Article
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Authors and funding
8 authors at 6 institutions in 1 country.
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Abstract
purposeUrinary calcium creatinine ratio (UCaCrR) is a reliable indicator for monitoring hypercalciuria following vitamin D supplementation. However, the reference range varies from region to region. Previous studies did not take vitamin D and parathyroid hormone status into account while evaluating UCaCrR. Hence, we undertook this study to establish the 95th percentile of UCaCrR as an indicator of hypercalciuria in North Indian children and adolescents.
methodsFour hundred seventy-three participants (boys 62.2%, girls 37.8%) with adequate dietary calcium intake, normal serum levels of 25-hydroxy-vitamin D (>20 ng/mL), and without secondary hyperparathyroidism following supplementation were selected for evaluation of UCaCrR.
resultsThe mean age and body mass index of subjects were 11.2±2.6 years and 18.0±3.6 kg/m2, respectively. The 95th percentile of UCaCrR in the study population was 0.126. The mean, median, and 95th percentile of UCaCrR was significantly higher in prepubertal children (age ≤10 years) (0.0586±0.0374, median=0.0548, 95th percentile=0.136) compared to those >10 years old (0.0503±0.0363, median=0.0407, 95th percentile=0.123, P=0.02). No significant difference in UCaCrR was observed between genders and different weight categories.
conclusionUCaCrR of 0.13 defines the cutoff value for hypercalciuria in North Indian children and adolescents with adequate dietary intake of calcium and sufficient serum vitamin D levels.
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