ArticlePLoS computational biology2019
A quick guide for student-driven community genome annotation.
Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Collaborative metabolic curation of an emerging model marine bacterium, Alteromonas macleodii ATCC 27126.PloS one · 2025Article
- Diaci v3.0: chromosome-level assembly, de novo transcriptome, and manual annotation of Diaphorina citri, insect vector of Huanglongbing.GigaScience · 2024Article
- Genome annotation: From human genetics to biodiversity genomics.Cell genomics · 2023Review
- Scientists without borders: lessons from Ukraine.GigaScience · 2022Article
- Genomic and Bioinformatic Resources for Perennial Fruit Species.Current genomics · 2022Review
- Annotation of glycolysis, gluconeogenesis, and trehaloneogenesis pathways provide insight into carbohydrate metabolism in the Asian citrus psyllid.GigaByte (Hong Kong, China) · 2022Article
- Annotation of putative circadian rhythm-associated genes inGigaByte (Hong Kong, China) · 2022Article
- Crowdsourcing biocuration: The Community Assessment of Community Annotation with Ontologies (CACAO).PLoS computational biology · 2021Article
- Insights from the first genome assembly of Onion (Allium cepa).G3 (Bethesda, Md.) · 2021Article
- Article
- Annotation ofGigaByte (Hong Kong, China) · 2021Article
- Undergraduate Virtual Engagement in Community Genome Annotation Provides Flexibility to Overcome Course Disruptions.Journal of microbiology & biology education · 2021Article
- Student biocuration projects as a learning environment.F1000Research · 2021Article
- Twelve quick steps for genome assembly and annotation in the classroom.PLoS computational biology · 2020Article
- G-OnRamp: Generating genome browsers to facilitate undergraduate-driven collaborative genome annotation.PLoS computational biology · 2020Article
- Using multiple reference genomes to identify and resolve annotation inconsistencies.BMC genomics · 2020Article
- Physiologists turned Geneticists: Identifying transcripts and genes for neuronal function in the Marbled Crayfish,Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2020Article
- Facilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience.Journal of microbiology & biology education · 2020Article
- Double triage to identify poorly annotated genes in maize: The missing link in community curation.PloS one · 2019Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental validation over the course of many years. The majority of gene models present in biological databases today have been identified in draft genome assemblies using automated annotation pipelines that are frequently based on orthologs from distantly related model organisms and usually have minor or major errors. Manual curation is time consuming and often requires substantial expertise, but is instrumental in improving gene model structure and identification. Manual annotation may seem to be a daunting and cost-prohibitive task for small research communities but involving undergraduates in community genome annotation consortiums can be mutually beneficial for both education and improved genomic resources. We outline a workflow for efficient manual annotation driven by a team of primarily undergraduate annotators. This model can be scaled to large teams and includes quality control processes through incremental evaluation. Moreover, it gives students an opportunity to increase their understanding of genome biology and to participate in scientific research in collaboration with peers and senior researchers at multiple institutions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.