Evidence map›Paper›PMID 30943106›Full record

ArticleMolecular biology of the cell2019

Promiscuity of the catalytic Sec7 domain within the guanine nucleotide exchange factor GBF1 in ARF activation, Golgi homeostasis, and effector recruitment.

Jay M Bhatt, William Hancock, Justyna M Meissner, Aneta Kaczmarczyk, Eunjoo Lee, Ekaterina Viktorova, Sasanka Ramanadham, George A Belov, Elizabeth Sztul

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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  7. Peptidylglycine α-amidating monooxygenase is required for atrial secretory granule formation.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jay M BhattDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
William HancockDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
Justyna M MeissnerDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
Aneta KaczmarczykDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
Eunjoo LeeDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
Ekaterina ViktorovaDepartment of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD 20742.
Sasanka RamanadhamDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
George A BelovDepartment of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD 20742.
Elizabeth SztulDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.
University of Alabama at Birmingham · USVirginia–Maryland College of Veterinary Medicine · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Role of host protein GBF1 in organizing enterovirus replication complexesR01AI125561 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI BELOV, GEORGE A. · 2016 to 2020
$1.9M
Spatio-temporal regulation of ARF signaling in vesicle formationR01GM122802 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SZTUL, ELIZABETH S · 2017 to 2020
$1.5M
NCI NIH HHS P30 CA013148NIAID NIH HHS R01 AI125561NIDDK NIH HHS P30 DK079626NIGMS NIH HHS R01 GM122802
6 · The paper itself

Abstract

The integrity of the Golgi and

Indexed as

Catalytic DomainHomeostasisADP-Ribosylation FactorsGolgi ApparatusGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsHeLa CellsHumanstrans-Golgi NetworkADP-Ribosylation Factorscytohesin-2GBF1 protein, humanGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsSec7 guanine nucleotide exchange factors

Identifiers

PMID30943106
PMCPMC6724685
OpenAlexW2934275657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.