Evidence map›Paper›PMID 30943067›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Genetic disruption of

Venkateswara Reddy Gogulamudi, Indra Mani, Umadevi Subramanian, Kailash N Pandey

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Renal Tubule Cell-SpecificHypertension (Dallas, Tex. : 1979) · 2026
    Article
  2. Podocyte cell-specificPhysiological genomics · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Depletion of cyclic-GMP levels and inhibition of cGMP-dependent protein kinase activate p21FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Venkateswara Reddy GogulamudiDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine , New Orleans, Louisiana.
Indra ManiDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine , New Orleans, Louisiana.
Umadevi SubramanianDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine , New Orleans, Louisiana.
Kailash N PandeyDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine , New Orleans, Louisiana.
Tulane University · US

Funding

Study of ANP Receptor:Gene Targeting and ExpressionR01HL062147 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI PANDEY, KAILASH N · 1998 to 2020
$5.0M
ANP RECEPTOR--MOLECULAR APPROACH OF SIGNALING MECHANISMSR01HL057531 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI PANDEY, KAILASH N · 1997 to 2013
$2.5M
ANP Receptor: Molecular approach of signaling mechanismsR56HL057531 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI PANDEY, KAILASH N · 2009 to 2009
$373k
NHLBI NIH HHS R01 HL057531NHLBI NIH HHS R01 HL062147NHLBI NIH HHS R56 HL057531
6 · The paper itself

Abstract

The present study was designed to determine the effects of gene knockout of guanylyl cyclase/natriuretic peptide receptor-A (GC-A/NPRA) on immunogenic responses affecting kidney function and blood pressure (BP) in

Indexed as

AnimalsBlood PressureCytokinesFemaleFibrosisImmunosuppressive AgentsInflammation MediatorsKidneyMice, Inbred C57BLMice, KnockoutReceptors, Atrial Natriuretic FactorSignal TransductionSirolimusT-Lymphocytes, RegulatoryToll-Like Receptor 2Toll-Like Receptor 4atrial natriuretic factor receptor ACytokinesImmunosuppressive AgentsInflammation MediatorsmTOR protein, mouseReceptors, Atrial Natriuretic FactorSirolimusTlr2 protein, mouseTlr4 protein, mouseToll-Like Receptor 2Toll-Like Receptor 4TOR Serine-Threonine Kinasescytokinesfibrosisgene targetingguanylyl cyclase receptornatriuretic peptidesrapamycinregulatory T cells

Identifiers

PMID30943067
PMCPMC6620590
OpenAlexW2928922361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.