ArticleJournal of veterinary internal medicine2019
Deleted in colorectal cancer (netrin-1 receptor) antibodies and limbic encephalitis in a cat with hippocampal necrosis.
Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Seizures in a cat with metabotropic glutamate receptor 1 (mGluR1) antibodies: a case report.Frontiers in veterinary science · 2026Article
- Complex partial seizures with orofacial involvement in 35 cats: MRI changes, cerebrospinal fluid analysis, voltage-gated potassium channel antibodies and survival.Journal of feline medicine and surgery · 2025Article
- Gliosarcoma associated with bilateral hippocampal sclerosis in a cat presenting complex partial seizures with orofacial involvement: A case report.Clinical case reports · 2024Article
- Case report: Antibodies to myelin basic protein in a podenco-crossbreed dog with seizures.Frontiers in veterinary science · 2024Article
- Parallel roles of neuroinflammation in feline and human epilepsies.Veterinary journal (London, England : 1997) · 2022Review
- Feline temporal lobe epilepsy: seven cases of hippocampal and piriform lobe necrosis in England and literature review.Journal of feline medicine and surgery · 2022Review
- Case Report: Anti-GABAFrontiers in veterinary science · 2022Article
- Postencephalitic epilepsy in dogs with meningoencephalitis of unknown origin: Clinical features, risk factors, and long-term outcome.Journal of veterinary internal medicine · 2020Article
- Deleted in colorectal cancer (netrin-1 receptor) antibodies and limbic encephalitis in a cat with hippocampal necrosis.Journal of veterinary internal medicine · 2019Article
- Investigation of the presence of specific neural antibodies in dogs with epilepsy or dyskinesia using murine and human assays.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 7-year-old neutered female domestic shorthaired cat born in Poland and then moved to Japan presented to the local clinic with recent onset of convulsive cluster seizures and status epilepticus. Magnetic resonance imaging revealed bilateral swelling of the hippocampus with T2 hyperintensity and contrast enhancing image, suggesting hippocampal necrosis. The cat completely recovered after treatment with antiepileptic drugs (AED) and administration of prednisolone (1 mg/kg PO q24h for 4 days and tapered). However, cluster seizures reoccurred and developed into status epilepticus despite increasing doses of AED. Although the convulsions were resolved by other AEDs, stupor and renal failure developed, and the cat was euthanized. Pathological findings were consistent with hippocampal necrosis. Immunological analysis for leucine-rich glioma inactivated 1 (LGI1) autoantibodies was negative, but antibodies against DCC (deleted in colorectal carcinoma) known as netrin-1 receptor were found. This report describes a case of feline autoimmune limbic encephalitis and hippocampal necrosis that were presumably associated with DCC autoantibodies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.