Evidence map›Paper›PMID 30942838›Full record

ArticleJAMA psychiatry2019

Association of Insulin Resistance With Schizophrenia Polygenic Risk Score and Response to Antipsychotic Treatment.

Jakub Tomasik, Santiago G Lago, Javier Vázquez-Bourgon, Sergi Papiol, Paula Suárez-Pinilla, Benedicto Crespo-Facorro, Sabine Bahn

Registry-linked trialOpen access · bronzeAbstract readLetter
In one paragraph

Article in JAMA psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07371325 (Efficacy of Pediococcus Acidilactici as add-on to Antipsychotic Drugs on Metabolic Syndrome Disturbances in First-episode Psychosis and Schizophrenia Spectrum Disorders. A Double-blind Placebo-controlled Trial.), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07371325 nacompletednot on this mapstarted 2024, after this paper: background citation

Efficacy of Pediococcus Acidilactici as add-on to Antipsychotic Drugs on Metabolic Syndrome Disturbances in First-episode Psychosis and Schizophrenia Spectrum Disorders. A Double-blind Placebo-controlled Trial.

TypeinterventionalSponsorManuel Jesús Cuesta ZuritaRan2024 to 2026Enrolled36ConditionsSCHIZOPHRENIA 1 (Disorder), Metabolic Abnormalities, Postbiotic SupplementArmsPediococcus acidilactici, pA1c®HI postbiotic supplementation taking participants, Atypical antipsychotics (AAP)
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Premature aging in serious mental illness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers.European archives of psychiatry and clinical neuroscience · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Genomic insights into the comorbidity between type 2 diabetes and schizophrenia.medRxiv : the preprint server for health sciences · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Jakub TomasikDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, England.
Santiago G LagoDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, England.
Javier Vázquez-BourgonUniversity Hospital Marqués de Valdecilla, IDIVAL, Department of Psychiatry, School of Medicine, University of Cantabria, Santander, Spain.
Sergi PapiolCentro de Investigación Biomédica en Red de Salud Mental, Barcelona, Spain.
Paula Suárez-PinillaUniversity Hospital Marqués de Valdecilla, IDIVAL, Department of Psychiatry, School of Medicine, University of Cantabria, Santander, Spain.
Benedicto Crespo-FacorroUniversity Hospital Marqués de Valdecilla, IDIVAL, Department of Psychiatry, School of Medicine, University of Cantabria, Santander, Spain.
Sabine BahnDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, England.
University of Cambridge · GBUniversidad de Cantabria · ESCentro de Investigación Biomédica en Red de Salud Mental · ESMarqués de Valdecilla University Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAntipsychotic AgentsFemaleFollow-Up StudiesGenetic Predisposition to DiseaseHumansInsulin ResistanceMaleMultifactorial InheritanceSchizophreniaAntipsychotic Agents

Identifiers

PMID30942838
PMCPMC6583823
OpenAlexW2934717350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.