ArticleArquivos brasileiros de cardiologia2019
Clinical Significance of Platelet Volume and Other Platelet Parameters in Acute Myocardial Infarction and Stable Coronary Artery Disease.
Article in Arquivos brasileiros de cardiologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 16 citations in OpenAlex.
- The mediating effect of DHA-mediated MPV improvement on coronary artery stenosis and its prognostic value.Frontiers in cardiovascular medicine · 2026Article
- Sex-specific machine learning models for cardiovascular disease risk prediction in adults aged ≥ 80 years: insights from the Chinese longitudinal healthy longevity survey.BMC geriatrics · 2025Article
- Is there a role for platelet indices in predicting poor glucoregulation in type 2 diabetes mellitus?World journal of diabetes · 2025Article
- The prognostic value of pulmonary hypertension in intensive care unit patients from Beth Israel Deaconess Medical Center (BIDMC).Journal of cardiothoracic surgery · 2025Article
- Simplified acute physiology score III is excellent for predicting in-hospital mortality in coronary care unit patients with acute myocardial infarction: A retrospective study.Frontiers in cardiovascular medicine · 2022Article
- Dynamic changes in platelets caused by shear stress in aortic valve stenosis.Clinical hemorheology and microcirculation · 2021Article
- The Search for New Prognosis Markers for Coronary Artery Disease.Arquivos brasileiros de cardiologia · 2019Article
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6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPlatelets are important in the initiation of thrombosis, and their morphological and functional changes are closely related with the occurrence and development of coronary artery thrombosis. Platelet parameters might be valuable in distinguishing between acute myocardial infarction (AMI) and stable coronary artery disease (SCAD).
objectiveThis study was designed to detect and compare changes in platelet parameters, such as mean platelet volume (MPV) in patients with acute myocardial infarction (AMI) and stable coronary artery disease (SCAD) and to investigate their roles in these diseases.
methodsSpecimen collection: Between January 2011 and December 2013, 2 mL of elbow vein blood was drawn from each of 31 patients primarily diagnosed with AMI, 34 SCAD patients and 50 healthy subjects; and placed in EDTA-K2 anticoagulant tubes. Platelet count (PLT), MPV, plateletcrit (PCT), platelet distribution width (PDW), white blood cell (WBC) and neutrophil (NEU) counts were determined using an STKS automated hematology analyzer (Beckman Courter).
resultsCompared with the control group, MPV levels were significantly higher in the AMI and SCAD groups (p < 0.05), while PLT was significantly lower (p < 0.05).
conclusionThese results suggest that MPV and other related parameters have a certain value in the diagnosis of SCAD and AMI.
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