Evidence map›Paper›PMID 30941580›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019

The ENHANCES study: a randomised controlled trial of a nurse-led survivorship intervention for patients treated for head and neck cancer.

Jane Turner, Patsy Yates, Lizbeth Kenny, Louisa G Gordon, Bryan Burmeister, Brett G M Hughes, Alexandra L McCarthy, Chris Perry, Raymond J Chan, Alana Paviour and 3 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Effects of self-management on quality of life in patients with head and neck cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Pooled it
  3. Nurse-led oral and maxillofacial oncology clinics: a review.The British journal of oral & maxillofacial surgery · 2021
    Pooled it
  4. Trial
  5. Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: main results of a cluster preference randomised controlled trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Trial
  6. Patient perspectives on nurse-led follow-up calls after head and neck surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Article
  8. Article
  9. An exploration of nursing and Allied Health Professional (AHP)-led post-treatment surveillance and survivorship care for people with head and neck cancer-a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jane TurnerFaculty of Medicine, University of Queensland, Brisbane, Australia. jane.turner@uq.edu.au.ORCID http://orcid.org/0000-0003-1438-217X
Patsy YatesQueensland University of Technology, Brisbane, Australia.
Lizbeth KennyFaculty of Medicine, University of Queensland, Brisbane, Australia.
Louisa G GordonQIMR Berghofer Medical Research Institute, Brisbane, Australia.
Bryan BurmeisterGenesisCare, Fraser Coast, Australia.
Brett G M HughesFaculty of Medicine, University of Queensland, Brisbane, Australia.
Alexandra L McCarthyPrincess Alexandra Hospital, Brisbane, Australia.
Chris PerryPrincess Alexandra Hospital, Brisbane, Australia.
Raymond J ChanQueensland University of Technology, Brisbane, Australia.
Alana PaviourRoyal Brisbane and Women's Hospital, Brisbane, Australia.
Helen SkermanQueensland University of Technology, Brisbane, Australia.
Martin BatstoneFaculty of Medicine, University of Queensland, Brisbane, Australia.
Lisa MackenzieFaculty of Medicine, University of Queensland, Brisbane, Australia.

Funding

National Health and Medical Research Council 1041640
6 · The paper itself

Abstract

purposeA randomised controlled trial was conducted to evaluate the effectiveness of a nurse-delivered Head and Neck Cancer Survivor Self-Management Care Plan (HNCP) for patients who had completed treatment for head and neck cancer (HNC).

methodsTen oncology nurses were trained to deliver the HNCP. The HNCP consisted of one face-to-face hour-long meeting in which the patient's treatment was recorded, as were contact details of health professionals involved in their care and follow-up schedules. Patients were guided to nominate up to three goals for their future well-being and assisted to devise an action plan to achieve these. The HNCP was given to the patient and a copy was forwarded to their primary care physician. One hundred and nine patients were randomised after definitive curative intent treatment, 36 to HNCP, 36 to receive information about survivorship, and 37 to usual care. The primary outcome, analysed by intention-to-treat, was change in quality of life measured by the FACT-H&N from baseline to 6-month follow-up.

resultsQuality of life of all groups decreased at 3 months but was close to baseline at 6 months. Compared with the usual care group, the only statistically significant mean difference at 6 months was for the information group on the physical well-being domain (mean difference 0.4, 95% - 1.8, 2.6, p < 0.05).

conclusionsA single-session nurse-delivered intervention is insufficient to improve the quality of life in HNC survivors compared with usual care. Provision of detailed written information about HNC survivorship is associated with improved physical well-being.

trial registrationACTRN12613000542796.

Indexed as

Cancer SurvivorsFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedNursesOncology NursingQuality of LifeSelf CareSelf EfficacyHead and neck cancerSelf-managementSurvivorship

Identifiers

PMID30941580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.