Evidence map›Paper›PMID 30941568›Full record

ReviewInternational journal of colorectal disease2019

Right-sided vs. left-sided obstructing colonic cancer: results of a multicenter study of the French Surgical Association in 2325 patients and literature review.

Diane Mege, Gilles Manceau, Laura Beyer, Valérie Bridoux, Zaher Lakkis, Aurélien Venara, Thibault Voron, Nicolas de'Angelis, Solafah Abdalla, Igor Sielezneff and 2 more

Abstract readMulticenter StudyReview
PubMed Publisher
In one paragraph

Review in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Bridge-to-surgery in acute right-sided obstructing colon cancer: A survey of surgeons' perspectives on treatment strategies.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
    Article
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  7. Review
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  13. Preoperative prognostic factors for obstructive colorectal cancer.International journal of colorectal disease · 2022
    Article
  14. Article
  15. Malignant Large Bowel Obstruction.Clinics in colon and rectal surgery · 2021
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Diane MegeAix-Marseille Université, Assistance Publique Hôpitaux de Marseille, Department of Digestive Surgery, Timone University Hospital, Marseille, France.
Gilles ManceauSorbonne Université, Assistance Publique Hôpitaux de Paris, Department of Digestive and Hepatopancreato-Biliary Surgery, Pitié Salpêtrière University Hospital, 47-83 Bd de l'Hôpital, 75651, Paris Cedex 13, France.
Laura BeyerNorth University Hospital, Marseille, France.
Valérie BridouxCharles Nicolle University Hospital, Rouen, France.
Zaher LakkisBesançon University Hospital, Besancon, France.
Aurélien VenaraAngers University Hospital, Angers, France.
Thibault VoronSaint Antoine University Hospital, Sorbonne University, Paris, France.
Nicolas de'AngelisHenri Mondor University Hospital, Université Paris-EST, Creteil, France.
Solafah AbdallaBicêtre University Hospital, Université Paris-Sud, Le Kremlin Bicetre, France.
Igor SielezneffAix-Marseille Université, Assistance Publique Hôpitaux de Marseille, Department of Digestive Surgery, Timone University Hospital, Marseille, France.
Mehdi KarouiSorbonne Université, Assistance Publique Hôpitaux de Paris, Department of Digestive and Hepatopancreato-Biliary Surgery, Pitié Salpêtrière University Hospital, 47-83 Bd de l'Hôpital, 75651, Paris Cedex 13, France. mehdi.karoui@aphp.fr.ORCID http://orcid.org/0000-0003-2644-7321
AFC (French Surgical Association) Working Group
Aix-Marseille Université · FRSorbonne Université · FRAssistance Publique Hôpitaux de Marseille · FRCentre Hospitalier Universitaire de Besançon · FRDélégation Paris 5 · FRHôpital Charles-Nicolle · FRUniversité d'Angers · FRUniversité Paris-Est Créteil · FRUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFew studies compared management and outcomes of obstructing colonic cancer (OCC), according to the tumor site. Our aim was to compare patient and tumor characteristics, postoperative and pathological results, and oncological outcomes after emergency management of right-sided vs. left-sided OCC.

methodsA national cohort study including all consecutive patients managed for OCC from 2000 to 2015 in French surgical centers members of the French National Surgical Association (AFC).

resultsDuring the study period, 2325 patients with OCC were divided in right-sided (n = 819, 35%) and left-sided (n = 1506, 65%) locations. Patients with right-sided OCC were older, more frequently females, and associated with comorbidities, history of cancer, or previous laparotomy. Surgical management was more frequently performed for right-sided than left-sided OCC (99 vs. 96%, p < 0.0001). Tumor resection was more frequently performed in right-sided OCC (95 vs. 90%, p < 0.0001). Among the resected patients, primary anastomosis was more frequently performed in case of right-sided OCC (86 vs. 62%, p < 0.0001). Definitive stoma rate was lower in right-sided location (17 vs. 46%, p < 0.0001). There was no significant difference between locations in terms of cumulative morbidity, anastomotic leak, unplanned reoperation, and mortality. Five-year overall and disease-free survival rates were significantly lower in right-sided OCC (43 and 36%) than in left-sided OCC (53 and 46%, p < 0.0001 and p = 0.001, respectively).

conclusionsAlthough patients with right-sided OCC are frailer than left-sided OCC, tumor resection and anastomosis are more frequently performed, without difference in surgical results. However, right-sided OCC is associated with worse prognosis than distal location.

Indexed as

AgedCohort StudiesColonic NeoplasmsDisease-Free SurvivalFemaleHumansMalePostoperative CareSurvival AnalysisTreatment OutcomeColonic obstructionEmergency surgeryLeft-sided obstructing colon cancerNational databaseRight-sided obstructing colon cancerSurvival

Identifiers

PMID30941568
OpenAlexW2932533032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.