ReviewPlant cell reports2019
Biochemistry and molecular biology of capsaicinoid biosynthesis: recent advances and perspectives.
Review in Plant cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 91 citations in OpenAlex.
- Light regulates capsaicinoid biosynthesis via the CaHY5-CaBBX2-CaACS8 module in pepper.The New phytologist · 2026Article
- Comprehensive Morpho-Functional Profiling of Peruvian AndeanPlants (Basel, Switzerland) · 2026Article
- Capsaicin for cardiometabolic syndrome: multitarget mechanisms and therapeutic potential.Frontiers in nutrition · 2026Review
- Spicy genes: mapping quantitative genomic regions and candidate genes for capsaicinoid and capsinoid biosynthesis in pepper.Frontiers in plant science · 2026Review
- Effect of Crosslinking Using Heat on the Physicochemical Features of Bsa-Capsaicin Nanoparticles.Pharmaceutics · 2025Article
- Unlocking the Alkaloid Biological Potential of Chili Pepper (Molecules (Basel, Switzerland) · 2025Review
- Functional interactions among H2O2, NO, H2S, and melatonin in the physiology, metabolism, and quality of horticultural Solanaceae.Journal of experimental botany · 2025Review
- Inheritance characteristics and potential of genomic prediction for pungency levels in FBreeding science · 2025Article
- Identification and characterization of a novel leakyMolecular breeding : new strategies in plant improvement · 2025Article
- Strategies to develop climate-resilient chili peppers: transcription factor optimization through genome editing.Planta · 2025Review
- Preharvest and Postharvest Applications of Fe-Based Nanomaterials: A Potent Strategy for Improving Pepper Storage.Nanomaterials (Basel, Switzerland) · 2025Article
- Detection and comparative analysis of VOCs between tomato and pepper based on GC×GC-TOFMS.Scientific reports · 2025Article
- Characterization of Thirty Germplasms of Millet Pepper (Metabolites · 2025Article
- Unlocking the potential of capsaicin in oral health (Review).Biomedical reports · 2024Review
- The Influence of Different Factors on the Metabolism of Capsaicinoids in Pepper (Plants (Basel, Switzerland) · 2024Review
- Carbon dioxide sensitization delays the postharvest ripening and fatty acids composition ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- High performance liquid chromatography (HPLC) based genetic diversity profiling of chilli germplasm for fruit pungency and phytochemical contents.BMC plant biology · 2024Article
- Phenolic Compounds and Capsaicinoids in ThreeMolecules (Basel, Switzerland) · 2023Article
- Effects of Storage Temperature at the Early Postharvest Stage on the Firmness, Bioactive Substances, and Amino Acid Compositions of Chili Pepper (Metabolites · 2023Article
- The GenusMolecules (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most widely known characteristic of chili pepper fruits is their capacity to produce capsaicinoids, which are responsible for the pungent sensation. The capsaicinoids have several uses in different areas, such as the pharmaceutical, cosmetic and agronomic industries, among others. They are synthesized by the condensation of vanillylamine (derived from phenylalanine) with a branched-chain fatty acid (from valine or leucine precursors), and they generally accumulate in the placental tissue of the chili pepper fruits. The pungency grade depends on the genotype of the plant but is also affected by external stimuli. In recent years, new structural and regulatory genes have been hypothesized to participate in the capsaicinoid biosynthetic pathway. Moreover, the role of some of these genes has been investigated. Substantial progress has been made in discerning the molecular biology of this pathway; however, many questions remain unsolved. We previously reviewed some aspects of the biochemistry and molecular biology of capsaicinoid biosynthesis (Aza-González et al. Plant Cell Rep 30:695-706. Aza-González et al., Plant Cell Rep 30:695-706, 2011), and in this review, we describe advances made by different researchers since our previous review, including the contribution of omics to the knowledge of this pathway.
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