Evidence map›Paper›PMID 30941485›Full record

Trial reportOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2019

Timeline of functional recovery after hip fracture in seniors aged 65 and older: a prospective observational analysis.

K Fischer, M Trombik, G Freystätter, A Egli, R Theiler, H A Bischoff-Ferrari

Registry-linked trialAbstract readObservational StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00133640 (Early Rehabilitation After Hip Fracture), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00133640 phase3unknown statusnot on this map

Early Rehabilitation After Hip Fracture: A Randomized Controlled Trial Comparing Different Vitamin D and Rehabilitation Programs

TypeinterventionalSponsorSwiss National Science FoundationRan2005 to 2008Enrolled204ConditionsAccidental Falls, Fractures, Hip FracturesArmscholecalciferol, Physiotherapy
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  10. LTE: from early gains to lasting outcomes-expanding ANP-led models for hip fracture recovery.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  11. Suicidal Ideation After Hip Fracture in Older Adults.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025
    Article
  12. Article
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  14. Association between reduced physical performance measures and short-term consequences after major emergency abdominal surgery: a prospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

K FischerDepartment of Geriatrics and Aging Research, Geriatric Clinic, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
M TrombikDepartment of Geriatrics and Aging Research, Geriatric Clinic, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
G FreystätterDepartment of Geriatrics and Aging Research, Geriatric Clinic, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
A EgliDepartment of Geriatrics and Aging Research, Geriatric Clinic, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
R TheilerDepartment of Geriatrics and Aging Research, Geriatric Clinic, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland.
H A Bischoff-FerrariDepartment of Geriatrics and Aging Research, Geriatric Clinic, University Hospital Zurich and University of Zurich, RAE B1, Rämistrasse 100, 8091, Zurich, Switzerland. Heike.Bischoff@usz.ch.
University of Zurich · CHStadtspital Waid · CHUniversity Hospital of Zurich · CH

Funding

Baugarten Stiftung No number availableSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung NFP-53Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung Professorship grant PP00B -114864Vontobel-Stiftung No number available
6 · The paper itself

Abstract

We investigated the timeline of functional recovery after hip fracture over 12 months in adults age ≥ 65 years using objective lower extremity function tests and subjective physical functioning. Objective functional recovery was largely complete in the first 6 months, whereas subjective recovery improved up to 9 months after hip fracture.

introductionHip fractures are a major cause of loss of function among seniors. We assessed the timeline of objective and subjective functional recovery after hip fracture.

methodsWe conducted a prospective observational secondary analysis of a 1-year clinical trial on vitamin D and home exercise treatment and complications after hip fracture among 173 patients age ≥ 65 years (mean age 84 years; 79.2% women; 77.4% community-dwelling) conducted from January 2005 through December 2007. Lower extremity function (Timed Up and Go test (TUG), knee extensor and flexor strength) and grip strength was assessed at baseline and at 6 and 12 months follow-up. Subjective physical functioning was assessed using the SF-36 questionnaire also at 3 and 9 months follow-up. Multivariable-adjusted repeated-measures models were used to assess the timeline of functional recovery in the total population and in subgroups of patients.

resultsLower extremity function including TUG (- 61.1%), knee extensor (+ 17.6%), and knee flexor (+ 11.6%) strength improved significantly in the first 6 months (P < 0.001). However, between 6 and 12 months, there was no further significant improvement for any of the functional tests. Grip strength decreased from baseline to 6 months (- 7.9%; P < 0.001) and from 6 to 12 months (- 10.8%; P < 0.001). Subjective physical functioning improved from 3 to 9 months (+ 15.2%, P < 0.001), but no longer thereafter.

conclusionsFunctional recovery after hip fracture may be largely complete in the first 6 months for objective functional tests, whereas may extend up to 9 months for subjective recovery, with oldest-old, female, institutionalized, and cognitively impaired patients recovering most poorly. CLINICAL TRIALS REGISTRY (ORIGINAL TRIAL): NCT00133640.

Indexed as

AgedAged, 80 and overBone Density Conservation AgentsCholecalciferolExercise TherapyFemaleFollow-Up StudiesHand StrengthHip FracturesHumansKnee JointLower ExtremityMalePostoperative PeriodProspective StudiesRecovery of FunctionBone Density Conservation AgentsCholecalciferolFunctional recoveryHip fractureObjective functional testsSubjective physical functioningTimeline

Identifiers

PMID30941485
OpenAlexW2934008781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.