ArticleImaging science in dentistry2019
Tc-99m hydroxymethylene diphosphonate scintigraphy, computed tomography, and magnetic resonance imaging of osteonecrosis in the mandible: Osteoradionecrosis versus medication-related osteonecrosis of the jaw.
Article in Imaging science in dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Identifying risk factors for osteoradionecrosis of the jaws: a systematic review and meta-analysis.Clinical oral investigations · 2026Pooled it
- Apparent diffusion coefficient for distinguishing between benign and malignant lesions in submandibular and sublingual spaces.Oral radiology · 2026Article
- Role of three-phase bone scintigraphy and fluorodeoxyglucose positron emission tomography in monitoring hyperbaric oxygen therapy combined with conservative surgery for refractory osteomyelitis.Journal of dental sciences · 2026Article
- Application of navigation system during surgery for medication-related osteonecrosis of the jaw.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2025Article
- The usefulness of different imaging modalities in mandibular osteonecrosis and osteomyelitis diagnosis.Scientific reports · 2025Article
- Analysis of bone single-photon emission CT/CT and diffusion-weighted MR imaging in medication-related osteonecrosis of the jaw: focusing on the correlation between standardized uptake values and apparent diffusion coefficient values.American journal of nuclear medicine and molecular imaging · 2024Article
- Maximum and mean standardized uptake values of medication-related osteonecrosis of the jaw with bone SPECT/CT: comparison of mandibular pathologies, control and temporomandibular joints.Dento maxillo facial radiology · 2023Article
- A computer program to assess the bone scan index for Tc-99m hydroxymethylene diphosphonate: evaluation of jaw pathologies of patients with bone metastases using SPECT/CTDiagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Article
- Medication-related osteonecrosis of the jaw in a patient with multiple myeloma: an unusual case with tumor in the surgical specimen.Oral radiology · 2022Article
- Clinical Diagnostic Imaging Study of Osteoradionecrosis of the Jaw: A Retrospective Study.Journal of clinical medicine · 2021Article
- Do various imaging modalities provide potential early detection and diagnosis of medication-related osteonecrosis of the jaw? A review.Dento maxillo facial radiology · 2021Review
- CBCT imaging and histopathological characteristics of osteoradionecrosis and medication-related osteonecrosis of the jaw.Imaging science in dentistry · 2021Article
- Assessment of inflammatory jaw pathologies using bone SPECT/CT maximum standardized uptake value.Dento maxillo facial radiology · 2020Article
- [Osteoradionecrosis of skull base: clinical analysis and experience].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020Article
- Clinical and panoramic radiographic features of osteomyelitis of the jaw: A comparison between antiresorptive medication-related and medication-unrelated conditions.Imaging science in dentistry · 2019Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo present characteristic findings of Tc-99m hydroxymethylene diphosphonate (HMDP) scintigraphy, computed tomography (CT), and magnetic resonance (MR) imaging for osteonecrosis in the mandible, especially osteoradionecrosis (ORN) and medication-related osteonecrosis of the jaw (MRONJ). MATERIALS AND
methodsThirteen patients with MRONJ and 7 patients with ORN in the mandible underwent Tc-99m HMDP scintigraphy, CT, and MR imaging (T1-weighted images [T1WI], T2-weighted images [T2WI], short inversion time inversion recovery images [STIR]), diffusion-weighted images [DWI], and apparent diffusion coefficient [ADC] mapping). The associations of scintigraphy, CT, and MR imaging findings with MRONJ and ORN were analyzed using the chi-square test with the Pearson exact test.
resultsThirteen patients with MRONJ and 7 patients with ORN in the mandible showed low signal intensity on T1WI and ADC mapping, high signal intensity on STIR and DWI, and increased uptake on scintigraphy. Periosteal bone proliferation on CT was observed in 69.2% of patients with MRONJ (9 of 13) versus 14.3% of patients with ORN (1 of 7) (
conclusionThis study presented characteristic imaging findings of MRONJ and ORN on scintigraphy, CT, and MR imaging. Our results suggest that CT can be effective for detecting MRONJ and ORN.
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