Evidence map›Paper›PMID 30940932›Full record

ReviewNature reviews. Immunology2019

T cell-mediated immunity to malaria.

Samarchith P Kurup, Noah S Butler, John T Harty

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 1 pooled it
25.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 1 synthesis or guideline pooled it, 245 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. The LEF1-LAG3 axis regulates CD4Parasites & vectors · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Overview of the host immune response toJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Review
  19. Regulatory T cell memory: implications for malaria.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Review
  20. Article

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samarchith P KurupDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
Noah S Butler *Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.ORCID http://orcid.org/0000-0002-1429-0796
John T Harty *Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA. john-harty@uiowa.edu.ORCID http://orcid.org/0000-0001-7266-2802
University of Iowa · US

Funding

Regulation of primary and secondary CD4 and CD8 T cell memoryR37AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2008 to 2017
$4.7M
T resident memory in the lungR01AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 1998 to 2023
$4.4M
Memory CD8 T cell immunity to Plasmodium liver stage infecR01AI085515 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2010 to 2020
$4.1M
Regulation of Plasmodium-specific CD4+ T CellsR01AI127481 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Noah Sullivan Butler · 2016 to 2026
$3.8M
Development and function of CD4+ memory T cells during malariaR01AI125446 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Noah Sullivan Butler · 2016 to 2026
$3.7M
Understanding immune regulation in blood-stage malariaR01AI100527 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2012 to 2021
$3.6M
T cell immunity to Plasmodium sporozoite immunizationR01AI095178 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2012 to 2016
$2.6M
CD8+ T Cell effector mechanisms against L. monocytogenesR21AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T. · 2002 to 2002
$331k
NIAID NIH HHS R01 AI042767NIAID NIH HHS R01 AI085515NIAID NIH HHS R01 AI095178NIAID NIH HHS R01 AI100527NIAID NIH HHS R01 AI125446NIAID NIH HHS R01 AI127481NIAID NIH HHS R21 AI042767NIAID NIH HHS R37 AI042767
6 · The paper itself

Abstract

Immunity to malaria has been linked to the availability and function of helper CD4

Indexed as

AnimalsCytokinesHumansMalariaMalaria VaccinesT-LymphocytesCytokinesMalaria Vaccines

Identifiers

PMID30940932
PMCPMC6599480
OpenAlexW2932322081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.