ArticleInternational journal of obesity (2005)2019
The relationship between body mass index and disability-free survival in elderly Japanese: the Ohsaki Cohort 2006 Study.
Article in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Are we giving too much weight to lean mass loss?Molecular metabolism · 2025Review
- Factors associated with ADL-defined disability-free survival among patients with advanced cancer in a palliative care setting: a retrospective cohort study.BMC palliative care · 2025Article
- Is a higher body mass index associated with longer duration of survival with disability in frail than in non-frail older adults?International journal of obesity (2005) · 2025Article
- Implication of grip strength assessment for the management of body weight in disability prevention in older adults.Journal of cachexia, sarcopenia and muscle · 2024Article
- Risk Factors of Long-Term Care Insurance Certification in Japan: A Scoping Review.International journal of environmental research and public health · 2022Article
- Contributors, risk associates, and complications of frailty in patients with chronic kidney disease: a scoping review.Therapeutic advances in chronic disease · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between body mass index (BMI) and disability-free survival (DFS) remains unclear.
methodsWe conducted a 10-year prospective cohort study of 12,666 Japanese individuals aged ≥ 65 y. Information on BMI and lifestyle factors was collected via a questionnaire in 2006. Functional disability data were retrieved from the public Long-term Care Insurance database. Subjects were divided into seven groups according to BMI (<19, 19-21, 21-23, 23-25, 25-27, 27-29 and ≥29). Fiftieth percentile differences (PDs) and 95% confidence intervals (CIs) in the DFS period (differences of period until the first 50% of the composite outcome (disability or death) occurred in each of the BMI groups) were calculated using the Laplace regression model.
resultsThere was a U-shaped relationship between BMI and the risk of incident composite outcome, with a BMI nadir of 25-27. Based on BMI 25-27 as a reference, the 50th PDs (95% CIs) (in months) in age at disability or death (median DFS) were -20.8 (-26.4, -15.2) (P < 0.001) months for BMI <19, -13.5 (-18.2, -8.7) (P < 0.001) months for BMI 19-21, -9.8 (-14.2, -5.4) (P < 0.001) months for BMI 21-23, -2.9 (-7.5, 1.7) (P = 0.21) months for BMI 23-25, -2.7 (-8.4, 2.9) (P = 0.34) months for BMI 27-29, and -11.5 (-19.6, -3.5) (P = 0.005) months for BMI ≥ 29. These relationships did not differ by sex.
conclusionOlder individuals with a BMI of <23 or ≥29 have a significantly shorter DFS period than those with a BMI of 25-27. It is suggested that the optimal BMI range for maximization of disability-free life expectancy in the elderly population is 23-29.
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