Evidence map›Paper›PMID 30940776›Full record

ArticleBioscience reports2019

LncRNA UCA1 acts as a sponge of miR-204 to up-regulate CXCR4 expression and promote prostate cancer progression.

Chang He, Xuwei Lu, Fan Yang, Liang Qin, Zhuifeng Guo, Yang Sun, Jiawen Wu

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
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  6. Crosstalk between long noncoding RNA and microRNA in Cancer.Cellular oncology (Dordrecht, Netherlands) · 2023
    Review
  7. Review
  8. Review
  9. Article
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  12. Long non-coding RNA in prostate cancer.American journal of clinical and experimental urology · 2022
    Review
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chang HeDepartment of Urology, Shanghai Minhang Hospital, Fudan University, Shanghai 200199, People's Republic of China.
Xuwei LuDepartment of Urology, Shanghai Minhang Hospital, Fudan University, Shanghai 200199, People's Republic of China.
Fan YangDepartment of Urology, Shanghai Minhang Hospital, Fudan University, Shanghai 200199, People's Republic of China.
Liang QinDepartment of Urology, Shanghai Minhang Hospital, Fudan University, Shanghai 200199, People's Republic of China.
Zhuifeng GuoDepartment of Urology, Shanghai Minhang Hospital, Fudan University, Shanghai 200199, People's Republic of China.
Yang SunDepartment of Urology, Shanghai Minhang Hospital, Fudan University, Shanghai 200199, People's Republic of China.
Jiawen WuDepartment of Urology, Shanghai Minhang Hospital, Fudan University, Shanghai 200199, People's Republic of China hcdoctor@hotmail.com.ORCID 0000-0002-7046-616X
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is a devastating malignant disease with a poor prognosis. The aim of current study is to investigate the role of lncRNA-urothelial carcinoma associated 1 (UCA1) in the progression of PCa. We evaluated the expression levels of UCA1 in a total of 16 benign prostatic hyperplasia tissues (BPH) and 40 PCa tissues, as well as PCa cells. The functional regulatory effects of UCA1 were investigated using a series of cell function approaches. Our data showed that UCA1 is frequently overexpressed in PCa tissues compared with BPH tissues (

Indexed as

Cell Line, TumorCell MovementCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansMaleMicroRNAsNeoplasm InvasivenessProstatic NeoplasmsReceptors, CXCR4RNA, Long NoncodingSignal TransductionCXCR4 protein, humanMicroRNAsMIRN204 microRNA, humanReceptors, CXCR4RNA, Long NoncodingUCA1 RNA, humanCXCR4miR-204prostate cancerUCA1

Identifiers

PMID30940776
PMCPMC6499452
OpenAlexW2935150783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.