Evidence map›Paper›PMID 30940641›Full record

ArticleDiabetes care2019

The Economic Burden of Elevated Blood Glucose Levels in 2017: Diagnosed and Undiagnosed Diabetes, Gestational Diabetes Mellitus, and Prediabetes.

Timothy M Dall, Wenya Yang, Karin Gillespie, Michelle Mocarski, Erin Byrne, Inna Cintina, Kaleigh Beronja, April P Semilla, William Iacobucci, Paul F Hogan

Registry-linked trialAbstract readComment
In one paragraph

Article in Diabetes care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04511468 (A Combination of Zinc, Chromium, Vitamin C, and Copper Supplement for Prediabetes Progression), which is not on this map. Cited by 125 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04511468 phase2active not recruitingnot on this mapstarted 2021, after this paper: background citation

A Combination of Zinc, Chromium, Vitamin C, and Copper Supplement for Prediabetes Progression: Randomized Controlled-Trial in Jakarta

TypeinterventionalSponsorIndonesia UniversityRan2021 to 2025Enrolled670ConditionsPreDiabetes, NutritionArmsZinc, Chromium, Vitamin C, and Copper Supplementation, Standard healthy lifestyle intervention, Placebo
3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Timothy M DallIHS Markit, Washington, DC tim.dall@ihsmarkit.com.ORCID http://orcid.org/0000-0001-5106-9401
Wenya YangLewin Group, Falls Church, VA.
Karin GillespieNovo Nordisk, Plainsboro, NJ.
Michelle MocarskiNovo Nordisk, Plainsboro, NJ.
Erin ByrneNovo Nordisk, Plainsboro, NJ.
Inna CintinaLewin Group, Falls Church, VA.
Kaleigh BeronjaLewin Group, Falls Church, VA.
April P SemillaIHS Markit, Washington, DC.
William IacobucciIHS Markit, Washington, DC.
Paul F HoganLewin Group, Falls Church, VA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was conducted to update national estimates of the economic burden of undiagnosed diabetes, prediabetes, and gestational diabetes mellitus (GDM) in the United States for year 2017 and provide state-level estimates. Combined with published estimates for diagnosed diabetes, these updated statistics provide a detailed picture of the economic costs associated with elevated blood glucose levels. RESEARCH DESIGN AND

methodsThis study estimated medical expenditures exceeding levels occurring in the absence of diabetes or prediabetes and the indirect economic burden associated with reduced labor force participation and productivity. Data sources analyzed included Optum medical claims for ∼5.8 million commercially insured patients continuously enrolled from 2013 to 2015, Medicare Standard Analytical Files containing medical claims for ∼2.8 million Medicare patients in 2014, and the 2014 Nationwide Inpatient Sample containing ∼7.1 million discharge records. Other data sources were the U.S. Census Bureau, Centers for Disease Control and Prevention, and Centers for Medicare & Medicaid Services.

resultsThe economic burden associated with diagnosed diabetes (all ages), undiagnosed diabetes and prediabetes (adults), and GDM (mothers and newborns) reached nearly $404 billion in 2017, consisting of $327.2 billion for diagnosed diabetes, $31.7 billion for undiagnosed diabetes, $43.4 billion for prediabetes, and nearly $1.6 billion for GDM. Combined, this amounted to an economic burden of $1,240 for each American in 2017. Annual burden per case averaged $13,240 for diagnosed diabetes, $5,800 for GDM, $4,250 for undiagnosed diabetes, and $500 for prediabetes.

conclusionsUpdated statistics underscore the importance of reducing the burden of prediabetes and diabetes through better detection, prevention, and treatment.

Indexed as

Diabetes, GestationalDiabetes MellitusPrediabetic StateAdultBlood GlucoseCost of IllnessFemaleHealth Care CostsHumansInfant, NewbornPregnancyUnited StatesBlood Glucose

Identifiers

PMID30940641
PMCPMC6702607

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.