Evidence map›Paper›PMID 30940636›Full record

ArticleBlood advances2019

Decellularized Wharton jelly matrix: a biomimetic scaffold for ex vivo hematopoietic stem cell culture.

Dandan Li, Grace Chiu, Brea Lipe, Richard A Hopkins, Jacquelyn Lillis, John M Ashton, Soumen Paul, Omar S Aljitawi

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. 3DACS biomaterials science & engineering · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Molecular regulation of hematopoietic stem cell quiescence.Cellular and molecular life sciences : CMLS · 2022
    Review
  10. Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Article
  12. In Vitro Modeling of Non-Solid Tumors: How Far Can Tissue Engineering Go?International journal of molecular sciences · 2020
    Review
  13. Use of Human Umbilical Cord and Its Byproducts in Tissue Regeneration.Frontiers in bioengineering and biotechnology · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dandan LiDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.
Grace ChiuHematology/Oncology and Bone Marrow Transplant Program, Department of Medicine, University of Rochester Medical Center, Rochester, NY.
Brea LipeHematology/Oncology and Bone Marrow Transplant Program, Department of Medicine, University of Rochester Medical Center, Rochester, NY.
Richard A HopkinsCardiac Surgery Research Laboratories, Children's Mercy Hospital and Clinics, Kansas City, MO; and.
Jacquelyn LillisGenomics Research Center, University of Rochester Medical Center, Rochester, NY.
John M AshtonGenomics Research Center, University of Rochester Medical Center, Rochester, NY.
Soumen PaulDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS.
Omar S AljitawiHematology/Oncology and Bone Marrow Transplant Program, Department of Medicine, University of Rochester Medical Center, Rochester, NY.
University of Rochester Medical Center · USUniversity of Kansas Medical Center · USChildren's Mercy Hospital · US

Funding

Novel Approaches for the Control of Microbial PathogensP30GM103326 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI YANKEE, THOMAS M. · 2012 to 2016
$5.3M
NIGMS NIH HHS P30 GM103326
6 · The paper itself

Abstract

Hematopoietic stem progenitor cells (HSPCs) reside in the bone marrow (BM) hematopoietic "niche," a special 3-dimensional (3D) microenvironment that regulates HSPC self-renewal and multipotency. In this study, we evaluated a novel 3D in vitro culture system that uses components of the BM hematopoietic niche to expand umbilical cord blood (UCB) CD34

Indexed as

Antigens, CD34BiomimeticsCell Culture TechniquesCell DifferentiationCell ProliferationFetal BloodHematopoietic Stem CellsHumansTissue ScaffoldsTransendothelial and Transepithelial MigrationWharton JellyAntigens, CD34

Identifiers

PMID30940636
PMCPMC6457237
OpenAlexW2934936030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.